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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC10390 [new locus tag: SPNOXC_RS05605 ]
  • pan locus tag?: PNEUPAN002295000
  • symbol: zmpA
  • pan gene symbol?: zmpA
  • synonym: iga
  • product: IgA-protease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC10390 [new locus tag: SPNOXC_RS05605 ]
  • symbol: zmpA
  • product: IgA-protease
  • replicon: chromosome
  • strand: +
  • coordinates: 1054833..1060592
  • length: 5760
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: FQ312027 (1054833..1060592) NCBI
  • BioCyc: see SPNOXC_RS05605
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
    ATGGAAAAGTATTTTGGTGAAAAACAAGAGCGTTTTTCATTTAGAAAATTATCAGTAGGA
    CTTGTATCTGCAACGATTTCAAGTTTATTTTTTATGTCTGTATTAGCTAGTTCATCTGTG
    GATGCTCAAGAAACTGCGGGAGTTCACTATAAATATGTGGCAGATTCAGAGCTATCATCA
    GAAGAAAAGAAGCAGCTTGTCTATGATATTCCGACATACGTGGAGAATGATGATGAAACT
    TATTATCTTGTTTATAAGTTAAATTCTCAAAATCAACTGGCGGAATTACCAAATACTGGA
    AGCAAGAATGAGAGGCAAGCCCTAGTTGCTGGTGCTAGCTTAGCTGCTCTGGGAATTTTA
    ATTTTTGCTGTTTCCAAGAAAAAGGTTAAGAATAAAACGGTATTACATTTAGTATTGGTT
    GCGGGAATAGGAAATGGTGTCTTAGTTTCAGTCCATGCTTTAGAAAATCATCTTTTGCTA
    AATTACAATACGGACTATGAATTGACCTCTGGAGAAAAATTACCTCTTCCTAAAGAGATT
    TCAGGTTACACTTATATTGGATATATCAAAGAGGGAAAAACGACTTCTGATTTTGAAGTA
    AGTAATCAAGAAAAATCAGCAGCCACTCCTACAAAACAACAAAAGGTGGATTATAATGTT
    ACACCAAATTTTGTAGACCATCCATCAACAGTACAAGCTATTCAGGAACAAACACCTGTT
    TCTTCAACTAAGCCGACAGAAGTTCAAGTAGTTGAAAAACCTTTCTCTACTAAATTAATC
    AATCCAAGAAAAGAAGAGAAACAATCTTCAGATTCTCAAGAACAATTAGCCGAACATAAG
    AATCTAGAAACGAAGAAAGAGGAGAAGATTTCTCCAAAAGAAAAGACTGGGGTAAATACA
    TTAAATCCACAGGATGAAGTTTTATCAGGTCAATTGAACAAACCTGAACTCTTATATCGT
    GAGGAAACTATAGAGACAAAAATAGATTTTCAAGAAGAAATTCAAGAAAATCCTGATTTA
    GCTGAAGGAACTGTAAGAGTAAAACAAGAAGGTAAATTAGGTAAGAAAGTTGAAATCGTC
    AGAATATTCTCTGTAAACAAGGAAGAAGTTTCGCGAGAAATTGTTTCAACTTCAACGACT
    GCGCCTAGTCCAAGAATAGTCGAAAAAGGTACTAAAAAAACTCAAGTTATAAAGGAACAA
    CCTGAGACTGGTGTAGAACATAAGGACGTACAGTCTGGAGCTATTGTTGAACCCGCAATT
    CAGCCTGAGTTGCCCGAAGCAGTAGTAAGTGATAAAGGCGTACCAGAAGTTCAACCAGCG
    TTATCGGAAGCAGTCGTAACCGACAAAGGTGAGACTGAGGTTCAACCAGAGTCGTCAGAT
    ACTGTGGTAAGTGATAAAGGTGAACCTAAACAGGTAGCACCGCTTCCAGAATATAAGGGT
    AATATTGAGCAAGTAAAACCTGAAACTCCGGTTGAGAAGACCAAAGAACAAGGTCCAGAA
    AAAACTGAAGAAGTTCCAGTAAAACCAACAGAAGAAACACCAGTAAATCCAAATGAAGGT
    ACTACAGAAGGAACCTCAATTCAAGGAGCAGAAAATCCAGTTCAACCTGCAGAAGAATCA
    ACAACGAATTCAGAGAAAGTATCACCAGATACATCTAGCGAAAATACTGGGGAAGTATCC
    AATAAACCTAGTGATTCAAAACCACCAGTTGAAGAATCAAATCAACCAGAAAATTCAGGT
    AATACAACATCAGAGAATGGACAAACAGAACCAGAACCATCAAACGGAAATTCAACTGAG
    AATGTTTCAACCAAATCAAACACATCCAATTCAAATGGAAACGAAGAAATTAAACAAGAA
    AATGAACTAGACCCCGATAAAAAGGTAGAAGATCCAGAGAAAACACTTGAATTAAGAAAT
    GTTTCCGACCTAGAGTTATACAGTTTGTCAAATGGTACTTATAAACAACACATTTCGTTA
    GAACAAGTTCCAAGCAATCCAAATAGCTACTTTGTTAAAGTGAAATCTTCTTCATTCAAA
    GATGTATACCTACCAGTAGCATCAATATCAGAGGAAAGAAAAAATGATAAAATCCTTTAT
    AAAATCACAGCAAAAGTAGAGAAGCTTCAGCAGGAGATAGAAAGCAGATATAAAGATAAT
    TTTACCTTCTATCTAGCTAAGAAGGGAACAGAAGAAACAACAAACTTTACTTCCTTTAGT
    AATCTGGTCAAAGCTATAAACCAAAATCTCTCTGGAACCTATCATTTAGGAGCTAGCCTG
    AATGCTAACGAAGTGGAGCTTAGTACTGATGATAAATCCTATATCAAGGGAACCTTTACT
    GGTCAGTTGATTGGTGAAAAAGATGGTAAGCATTATGCTATTTACAACTTGAAAAAGCCT
    CTTTTTGAAAGCTTGAGAGGGGCCACAATAGAAAAGTTGAGTCTGAAAAATGTCTCTATT
    TCAGGGAAAGATGATATCGGTTCACTGGCAAATGAAGCTCAGAATAACACAAAAATTAAG
    CAAGTTCATGTGGATGGTGTACTTGCCGGTGAACGTGGTATCGGTGGTTTGTTGGCTAAG
    GCAGATCAATCAAGCATCACAGAGAGTAGTTTCAAGGGAAGAATTGTCAATACCTATGAA
    ACAACCGCTTCCTATAATATCGGTGGCCTGGTCGGTCATTTGACAGGAAGCAAAGCTTCA
    CTGACTAAGTCAAAAGCGACAGTGGTCATTTCATCAAATACAAATAGTTCTGACCAGACC
    GTTGGAGGTATCGCTGGTCTTGTAGACAAAGATGCGCATATTCAGAATAGCTATTCTGAA
    GGGGATATTAATAATAGTCAACGTTTTGGAAAAGTTGCTGGTATAGCAGGTAACTTATGG
    GATCGTGAATCAAATAGTGAAAATCATGCTGGAAGATTGACTAATGTGCTTAGTGATGTC
    AATGTAACTAATGGAAATGCCATTAGTGGTTACCATTATAATGGAATGAAAATTACTGAT
    GCATTTAGTAATAAAGCGAATAAAGTTTTCAATGTCACTTTAGAGAAGGATGAGGTCGTC
    AGCAAAGAATCCTTTGAGGAAAGAGGAACAATGCTAGATGCTTCTCAAATTGCAAGCAAA
    AAAGCAGAAATCAATCTTCTCACTCCACCAATAGTGAAACCCCTCTCAACAAGCGGTAAG
    AAAGACAGTGATTTTTCTAAGATAGCCCATTATCAAGCCAACCGTGCTTTGGTTTATAAG
    AACATTGAAAAATTGTTACCTTTCTATAACAAGGCGACCATCGTGAAATACGGAAACCTG
    GTTAAGGAGAACAGTATCTTATATCAAAAAGAACTCTTGTCTGCAGTTATGATGAAGGAT
    GACCAAGTAATCACAGATATTATTTCCAACAAACAGACTGCAAACAAACTCTTGCTTCAC
    TACAAGGACCATTCATCTGAAAAGTTTGATCTCAGGTACCAGGCTGATTTTGCTAAGTTA
    GCAGAATATAGTCTAGGAGATACTGGTCTTCTCTATACGCCAAACCAATTCTTGTATGAC
    CAAGACTCTATCATCAATCAAGTTTTACCTGAATTACAGCAGGTTGCCTACGATTCAGAA
    GCTATCAGAAAGACACTCGGAATTTCTCCAGAGGTCAAGCAAACTGAGCTCTATATGGAA
    GACCAGTTTACCAAAACAAAGCAAGATTTGGCAAACAGTTTGAAAAAACTCTTGTCTGCA
    GATGCTGGACTTGCTGGTGACAACCCAGTTACCAGAGGCTATCTTGTAGATAAAATCAAG
    AACAATAAGGAAGCCTTACTACTCGGTTTAACTTATTTAGAACGTTGGTATAACTTTAGC
    TATGGTCAAGTGAATGTCAAAAACCTAGTTATGTATCATCTGGACTTCTTTGGTAAAGGA
    AATACCTCACCATTAGATACTCTGATTGAGTTAGGTAAATCTGGCTTTAACAATCTTCTT
    GCTAAAAACAATGTCGATACTTATGCTATCAGTCTTGCCAGCCATCATGGAACGACAGAT
    TTGTTTAGCACGTTGGAAAATTACCGAAAAGTCTTTCTACCAGACAAAACCAATAATGAC
    TGGTTTAAATCACAGACTAAGGCTTACATTGTCGAAGAAAAATCCAATATCGAAGAGGTG
    AAAACGAAGCAAGGACTAGTTGGTACTAAGTATTCTATTGGTGTCTATGATCGAATCACT
    AGCGACAGCTGGAAATACCGTAATATGGTACTACCTCTACTTACCTTGCCAGAAAGATCC
    GTATTTGTCATTTCAACCATATCTAGTCTAGGTTTTGGTGCTTATGATCGCTATCGTAAT
    AAAGAACATCAAGCAAATGGTGATCTTAATAGCTTTGTTGAAAAGAGTGCTCACGAAACA
    GCAGAGCGTCAACGAGATCACTATGATTATTGGTATCGTATTCTAGATGAAAAAGGGCGT
    GAAAAGCTTTATCGAAATATCTTGCTTTATGATGCCTATAAATTTGGAACTGATCATACT
    GAAGGAAAGGCTACAGAAGTAGCAAATTTTGATAATCCAAATCCTGCAATGAAACATTTC
    TTTGGACCTGTTGGAAATAAGGTTGGACATAATGGACATGGTGCTTATGCTACAGGGGAT
    GCCGTTTATTATATGGGTTATCGTATGTTGGACAAGGACGGCGCCATTACTTATACGCAT
    GAGATGACACATGACTCAGATCAGGACATTTATCTTGGAGGTTATGGAAGAAGAAGTGGA
    CTTGGACCTGAGTTCTTTGCTAAAGGCTTACTACAAGCACCAGACCAACCAAGTGATGCA
    ACCATTACCATCAACTCTATCTTGAAACATAAAACATCAGATAGTACAGAAGGTCAGCGA
    TTGCAAGTACTTGATCCAACTACAAGATTTAATGACGCAGCAGATCTTCAGAACTACGTC
    CACAATATGTTTGATGTCGTTTACATGTTGGAATATCTCGAAGGGCAATCTATCGTGAAA
    CAGTTAGATGCTTATCAGAAAATGACGGCCCTGAGAAAAATCGAGAATAAATACGTGAAA
    GATCCTGCAGATGGAAATGATGTTTATGCTACTAATGTTGTGAAAAATTTGACTGAAGAT
    GAAGCTAAAAAATTGACGAGCTTTGATAGTTTGATTGACAATAACATTCTTTCGGCTCGT
    GAGTATAAGGCTGGCACTTATGAGAGAAATGGCTACTTTACTATAAAACTCTTTGCACCA
    ATCTTTTCAGCATTGAGCAGTGAGAAAGGAACTCCAGGCGACCTTATGGGACGTCGTATA
    GCCTATGAACTACTAGCTGCTAAAGGCTTTAAAGATGGTATGGTACCATATATCTCAAAT
    CAATACGAAGAAGATGCTAAACAACAAGGGCAAACTATCAATCTTTATGGTAAAGAACGG
    GGCTTGGTGACCGATGAGCTTGTTTTGAAAAAGGTATTTGATGGTAAGTATAAAACTTGG
    GCAGAATTTAAGACAGCTATGTACCAAGAACGGGTGGATCAGTTTGGAAACTTGAAGCAG
    GTGACCTTTAAAGATCCGACAAAACGATGGCCAAGCTATGGCACAAAGACTATCAATAAT
    GTGGATGAATTGCAGAAACTAATGGATGAAGCTGTTTTGCAGGATGCTACAGGTACACGT
    TGGAGTAATTATAATCCAGAAATAGACAGTGCAGTTCATAAGTTGAAGAGAGCAATCTTT
    AAAGCCTATCTTGCTCAAACCAATGATTTTAGAAGTTCAATTTTTGAGAATAAAAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
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    660
    720
    780
    840
    900
    960
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    1380
    1440
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    1560
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    1920
    1980
    2040
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    2160
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    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
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    4620
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    4860
    4920
    4980
    5040
    5100
    5160
    5220
    5280
    5340
    5400
    5460
    5520
    5580
    5640
    5700
    5760

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC10390 [new locus tag: SPNOXC_RS05605 ]
  • symbol: ZmpA
  • description: IgA-protease
  • length: 1919
  • theoretical pI: 5.39069
  • theoretical MW: 213969
  • GRAVY: -0.653153

⊟Function[edit | edit source]

  • TIGRFAM:
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 44.5)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 21.7)
  • TheSEED  :
    • IgA-specific metalloendopeptidase (EC 3.4.24.13)
  • PFAM:
    no clan defined Peptidase_M26_C; M26 IgA1-specific Metallo-endopeptidase C-terminal region (PF07580; HMM-score: 1067.5)
    and 5 more
    Peptidase_M26_N; M26 IgA1-specific Metallo-endopeptidase N-terminal region (PF05342; HMM-score: 271.5)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 55.2)
    no clan defined Glug; The GLUG motif (PF07581; HMM-score: 41.1)
    YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 36.1)
    Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 29.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 2
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.0059
    • Cell wall & surface Score: 0.8489
    • Extracellular Score: 0.1451
  • SignalP: Signal peptide SP(Sec/SPI) length 42 aa
    • SP(Sec/SPI): 0.91723
    • TAT(Tat/SPI): 0.067255
    • LIPO(Sec/SPII): 0.005174
    • Cleavage Site: CS pos: 42-43. VDA-QE. Pr: 0.9143
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW32695 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLLNYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTKLINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEIQENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTKKTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSEAVVTDKGETEVQPESSDTVVSDKGEPKQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSPDTSSENTGEVSNKPSDSKPPVEESNQPENSGNTTSENGQTEPEPSNGNSTENVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLELRNVSDLELYSLSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEIESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNLSGTYHLGASLNANEVELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFESLRGATIEKLSLKNVSISGKDDIGSLANEAQNNTKIKQVHVDGVLAGERGIGGLLAKADQSSITESSFKGRIVNTYETTASYNIGGLVGHLTGSKASLTKSKATVVISSNTNSSDQTVGGIAGLVDKDAHIQNSYSEGDINNSQRFGKVAGIAGNLWDRESNSENHAGRLTNVLSDVNVTNGNAISGYHYNGMKITDAFSNKANKVFNVTLEKDEVVSKESFEERGTMLDASQIASKKAEINLLTPPIVKPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVKENSILYQKELLSAVMMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFAKLAEYSLGDTGLLYTPNQFLYDQDSIINQVLPELQQVAYDSEAIRKTLGISPEVKQTELYMEDQFTKTKQDLANSLKKLLSADAGLAGDNPVTRGYLVDKIKNNKEALLLGLTYLERWYNFSYGQVNVKNLVMYHLDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLASHHGTTDLFSTLENYRKVFLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSDSWKYRNMVLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLNSFVEKSAHETAERQRDHYDYWYRILDEKGREKLYRNILLYDAYKFGTDHTEGKATEVANFDNPNPAMKHFFGPVGNKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDQPSDATITINSILKHKTSDSTEGQRLQVLDPTTRFNDAADLQNYVHNMFDVVYMLEYLEGQSIVKQLDAYQKMTALRKIENKYVKDPADGNDVYATNVVKNLTEDEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAPIFSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKRWPSYGTKTINNVDELQKLMDEAVLQDATGTRWSNYNPEIDSAVHKLKRAIFKAYLAQTNDFRSSIFENKK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Jeffrey N Weiser, Deborah Bae, Claudine Fasching, Ronald W Scamurra, Adam J Ratner, Edward N Janoff
Antibody-enhanced pneumococcal adherence requires IgA1 protease.
Proc Natl Acad Sci U S A: 2003, 100(7);4215-20
[PubMed:12642661] [WorldCat.org] [DOI] (P p)Damiana Chiavolini, Guido Memmi, Tiziana Maggi, Francesco Iannelli, Gianni Pozzi, Marco R Oggioni
The three extra-cellular zinc metalloproteinases of Streptococcus pneumoniae have a different impact on virulence in mice.
BMC Microbiol: 2003, 3;14
[PubMed:12841855] [WorldCat.org] [DOI] (I e)E N Janoff, J B Rubins, C Fasching, D Charboneau, J T Rahkola, A G Plaut, J N Weiser
Pneumococcal IgA1 protease subverts specific protection by human IgA1.
Mucosal Immunol: 2014, 7(2);249-56
[PubMed:23820749] [WorldCat.org] [DOI] (I p)H Lomholt
Evidence of recombination and an antigenically diverse immunoglobulin A1 protease among strains of Streptococcus pneumoniae.
Infect Immun: 1995, 63(11);4238-43
[PubMed:7591053] [WorldCat.org] [DOI] (P p)K Poulsen, J Reinholdt, M Kilian
Characterization of the Streptococcus pneumoniae immunoglobulin A1 protease gene (iga) and its translation product.
Infect Immun: 1996, 64(10);3957-66
[PubMed:8926055] [WorldCat.org] [DOI] (P p)J H Wani, J V Gilbert, A G Plaut, J N Weiser
Identification, cloning, and sequencing of the immunoglobulin A1 protease gene of Streptococcus pneumoniae.
Infect Immun: 1996, 64(10);3967-74
[PubMed:8926056] [WorldCat.org] [DOI] (P p)

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