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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_0948 [new locus tag: SP_RS04690 ]
  • pan locus tag?: PNEUPAN001936000
  • symbol: SP_0948
  • pan gene symbol?: phoH
  • synonym:
  • product: PhoH family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_0948 [new locus tag: SP_RS04690 ]
  • symbol: SP_0948
  • product: PhoH family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 896905..897873
  • length: 969
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    TTGAAGGAACATTCAATAGACATTCAACTGAGTCATCCAGATGACCTGTTTCATCTTTTT
    GGTTCCAATGAACGCCATCTTCGTTTGATGGAAGAAGAGCTTGATGTTGTGATTCATGCT
    CGTACGGAGATTGTCCAGGTTTTGGGAGAAGAGTCTGCCTGTGAGGAAGCCCGTCAAGTT
    ATTCAGGCTTTGATGGTCTTGGTAAATCGTGGGATGACCGTTGGTACGCCAGATGTAGTC
    ACTGCGATTAGCATGGTCAAAAATGATGAAATTGACAAGTTTGTCGCCCTTTACGAAGAA
    GAAATTATCAAGGATAATACTGGGAAACCTATCCGTGTCAAAACCCTAGGGCAAAAGCTT
    TATGTGGACAGTGTCAAACAGCATGATGTGACCTTTGGAATTGGGCCAGCAGGTACAGGG
    AAGACCTTCCTTGCAGTGACCTTGGCAGTGACTGCCCTTAAACGTGGGCAAGTCAAGCGA
    ATTATCCTAACTCGTCCAGCGGTGGAAGCGGGAGAGAGTCTTGGATTTCTTCCGGGTGAT
    CTTAAGGAGAAGGTGGATCCTTACCTTCGTCCTGTTTACGATGCCTTGTATCAAATTCTT
    GGGAAAGACCAAACGACTCGTCTCATGGAGCGTGAAATTATCGAAATTGCGCCCCTTGCC
    TATATGCGTGGCCGGACCTTGGATGATGCCTTTGTCATTCTCGATGAGGCGCAAAACACG
    ACCATCATGCAGATGAAGATGTTCTTGACGCGTTTAGGTTTTCATTCTAAGATGATTGTC
    AATGGAGATATTAGTCAGATTGACCTGCCACGTAATGTCAAGTCCGGTTTGATTGATGCT
    CAAGAGAAACTCAAGAACATCCATCAGATTGACTTTGTTCATTTTTCAGCCAAGGATGTG
    GTTCGCCATCCTGTTGTCGCTCAGATTATCCGAGCCTATGAATATTCTACTGAAGTTGCA
    CACGACTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    969

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_0948 [new locus tag: SP_RS04690 ]
  • symbol: SP_0948
  • description: PhoH family protein
  • length: 322
  • theoretical pI: 5.97086
  • theoretical MW: 36270.7
  • GRAVY: -0.106832

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair putative DNA helicase (TIGR00376; EC 3.6.4.12; HMM-score: 15.9)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair exodeoxyribonuclease V, alpha subunit (TIGR01447; EC 3.1.11.5; HMM-score: 15.7)
  • TheSEED  :
    • PhoH-like protein, PhoL
    Phosphorus Metabolism Phosphorus Metabolism - no subcategory Phosphate metabolism  Phosphate starvation-inducible protein PhoH, predicted ATPase
  • PFAM:
    P-loop_NTPase (CL0023) PhoH; PhoH-like protein (PF02562; HMM-score: 318.3)
    and 7 more
    AAA_30; AAA domain (PF13604; HMM-score: 27.6)
    AAA_19; AAA domain (PF13245; HMM-score: 24.5)
    IstB_IS21; IstB-like ATP binding protein (PF01695; HMM-score: 23.1)
    AAA_22; AAA domain (PF13401; HMM-score: 21.1)
    AAA_25; AAA domain (PF13481; HMM-score: 16.3)
    Zot; Zonular occludens toxin (Zot) (PF05707; HMM-score: 15.6)
    UvrD-helicase; UvrD/REP helicase N-terminal domain (PF00580; HMM-score: 15.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9653
    • Cytoplasmic Membrane Score: 0.0285
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0061
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002196
    • TAT(Tat/SPI): 0.000162
    • LIPO(Sec/SPII): 0.000173
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEIVQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEIIKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKRIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAPLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSGLIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site: 896877 [1]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ 1.0 1.1 1.2 Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
    The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
    PLoS Pathog: 2018, 14(12);e1007461
    [PubMed:30517198] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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