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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 19-NOV-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae A66
  • locus tag: A66_00463 [new locus tag: A66_RS02325 ]
  • pan locus tag?: PNEUPAN001382000
  • symbol: A66_00463
  • pan gene symbol?: endoD
  • synonym:
  • product: Endo-beta-N-acetylglucosaminidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: A66_00463 [new locus tag: A66_RS02325 ]
  • symbol: A66_00463
  • product: Endo-beta-N-acetylglucosaminidase
  • replicon: chromosome
  • strand: +
  • coordinates: 438101..443008
  • length: 4908
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: LN847353 (438101..443008) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0444 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

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    ATGATTGGTGCTGTTTTATTTGCTGGTCCAGCCTTGGCTGAAGAAACTGCAGTTCCTGAA
    AATAGCGGAGCTAATACAGAGCTTGTTTCAGGAGAGAGTGAGCATTCGACCAATGAAGCT
    GATAAGCAGAATGAAGGGGAACATGCTAGAGAAAACAAGCTAGAAAAGGCAGAAGGAGTA
    GCGACAGCATCTGAAACTGCTTCGCCAGCAAGCAATGAAGCTGCAACTACTGAAACTGCA
    GAAGCAGCTAGCGCAGCTAAACCAGAGGAAAAAGCAAGTGAGGTGGTTGCAGAAACACCA
    TCTGCAGAAGCAAAACCTAAGTCTGACAAGGAAACAGAAGCAAAGCCCGAAGCAACTAAC
    CAAGGGGATGAGTCTAAACCAGCAGAAGAAGCTAATAAGACTGAAAAAGAAGTCCAGCCA
    GATGTCCCTAAAAATACAGAAAAAACATTAAAACCAAAGGAAATCAAATTTAATTCTTGG
    GAAGAATTGTTAAAATGGGAACCAGGTGTTCGTGAAGATGATGCTATTAACCGCGGATCT
    GTTGTCCTCGCTTCACGTCGGACAGGTCATTTAGTCAATGAAAAAGCTAGCAAGGAAGCA
    AAAGTTCAAACCTTATCAAACACTAATTCTAAAGCAAAAGACCATGCTTCTGTTGGTGGA
    GAAGAGTTCAAGGCCTATGCTTTTGACTATTGGCAATATCTAGATTCAATGGTCTTCTGG
    GAAGGTCTCGTACCAACTCCTGACGTTATTGATGCAGGTCACCGTAACGGGGTTCCTGTA
    TACGGTACACTCTTCTTCAACTGGTCTAATAGTATTGCAGATCAAGAAAGATTTGCTGAA
    GCTTTGAAGCAAGACGCAGATGGTAGCTTCCCAATTGCTCGTAAATTGGTAGACATGGCA
    AAGTATTATGGCTATGATGGCTATTTCATCAACCAAGAAACAACTGGAGATTTGGTTAAA
    CCTCTTGGAGAAAAGATGCGCCAGTTTATGCTCTATAGCAAGGAATATGCTGCTAAGGTA
    AACCATCCAATCAAGTATTCTTGGTATGATGCCATGACCTATAACTATGGACGTTACCAT
    CAAGATGGTTTGGGAGAATACAACTACCAATTCATGCAACCAGAAGGAGATAAGGTTCCG
    GCAGATAACTTCTTTGCTAACTTTAACTGGGATAAGGCTAAAAATGATTACACTATTGCA
    ACTGCCAACTGGATTGGTCGTAATCCTTATGATGTATTTGCAGGTTTGGAATTGCAACAG
    GGTGGTTCCTACAAGACAAAGGTTAAGTGGAATGACATTTTAGACGAAAATGGGAAATTA
    CGCCTTTCTCTTGGTTTATTTGCCCCAGATACCATTACAAGTTTAGGAAAAACTGGTGAA
    GATTATCATAAAAATGAAGATATCTTCTTTACAGGTTATCAAGGAGACCCCACTGGCCAA
    AAACCAGGTGACAAAGATTGGTATGGTATTGCTAACCTAGTTGCGGACCGTACGCCAGCG
    GTAGGTAATACTTTTACTACTTCTTTTAATACAGGTCATGGTAAAAAATGGTTCGTAGAT
    GGTAAGGTTTCTAAGGATTCTGAGTGGAATTATCGTTCAGTATCAGGTGTTCTTCCAACA
    TGGCGCTGGTGGCAGACTTCAACAGGGGAAAAACTTCGTGCAGAATATGATTTTACAGAT
    GCCTATAATGGCGGAAATTCCCTTAAATTCTCTGGTGATGTAGCCGGTAAGACAGATCAG
    GATGTGAGACTTTATTCTACTAAGTTAGAAGTAACTGAGAAGACCAAACTTCGTGTTGCC
    CACAAGGGAGGAAAAGGTTCTAAAGTTTATATGGCATTCTCTACAACTCCAGACTACAAA
    TTCGATGATGCAGATGCATGGAAAGAGCTAACCCTTTCTGACAACTGGACAAATGAAGAA
    TTTGCTCTCAGCTCACTAGCGGGTAAAACCATCTATGCAGTCAAACTATTTTTCGAGCAT
    GAAGGTGCTGTAAAAGATTATCAGTTCAACCTAGGACAATTAACTATCTCGGACAATCAC
    CAAGAGCCACAATCGCCGACAAGCTTTTCTGTAGTGAAACAATCGCTTAAAAATGCCCAA
    GAAGCGGAAGCAGTTGTGCAATTTAAAGGCAACAAGGATGCAGATTTCTATGAAGTTTAT
    GAAAAAGATGGAGACAGCTGGAAATTACTAACTGGCTCATCTTCTACAACTATTTATCTA
    CCAAAAGTTAGCCGCTCAGCAAGTGCTCAGGGTACAACTCAAGAACTGAAGGTTGTAGCA
    GTCGGTAAAAATGGAGTTCGTTCAGAAGCTGCAACCACAACCTTTGATTGGGGTATGACT
    GTAAAAGATACCAGCCTACCAAAACCACTAGCTGAAAATATCGTTCCAGGTGCAACAGTT
    ATTGATAGTACTTTCCCTAAGACTGAAGGTGGAGAAGGTATTGAAGGTATGTTGAACGGT
    ACCATTACTAGCTTGTCAGATAAATGGTCTTCAGCTCAGTTGAGTGGTAGTGTGGATATT
    CGTTTGACCAAGCCACGTACCGTTGTTAGATGGGTCATGGATCATGCAGGAGCTGGTGGT
    GAGTCTGTTAACGATGGCTTGATGAACACCAAAGACTTTGACCTTTATTATAAAGATGCA
    GATGGTGAGTGGAAGCTAGCTAAGGAAGTCCGTGGTAACAAAGCACACGTGACAGATATC
    ACTCTTGATAAACCAATCACTGCTCAAGACTGGCGCTTGAATGTTGTCACTTCTGACAAT
    GGAACTCCATGGAAGGCTATTCGTATCTATAACTGGAAAATGTATGAAAAGCTTGATACT
    GAGAGTGTCAATATTCCGATGGCCAAGGCTGCAGCCCGTTCTCTAGGCAATAACAAGGTA
    CAAGTTGGCTTTGCAGATGTACCGGCTGGAGCAACTATTACCGTTTATGATAATCCAAAT
    TCTCAAATTCCGCTCGCAACCTTGAAGAGCGAAGTTGGAGGAGACCTAGCAAGTGCACCA
    TTGGATTTGACAAATCAATCTGGTCTTCTTTATTATCGTACCCAGTTGCCAGGCAAGGAA
    ATTAGTAATGTCCTAGCAGTTTCCGTTCCAAAAGATGACAGAAGAATCAAGTCAGTCAGC
    CTAGAAACAGGACCTAAGAAAACAAGCTACGCCGAAGGGGAGGATTTGGACCTTAGAGGT
    GGTGTTCTTCAAGTTCAGTATGAAGGAGGAACTGAGGACGAACTCATTCGCCTAACTCAC
    GCAGGTGTATCAGTATCAGGTTTTGATACGCATCATAAGGGAGAACAGAATCTTACTCTC
    CAATATTTGGGACAACCAGTAAATGCTAATTTGTCAGTGACTGTCACTGGCCAAGATGAA
    GCAAGTCCGAAAACTATTTTGGGAATTGAAGTAAGTCAGGAACCGAAAAAAAATTACCTA
    GTTGGTGATAGCTTAGACTTGTCTGAAGGATGCTTTGCAGTGGCTTATAGCAATGACACC
    ATGGAAGAACATTCCTTTACTGATGAGGGAGTTGAAATTTCTGGTTACGATGCTCAAAAG
    ACTGGTCGTCAAACCTTGACGCTTCGTTACCAAGGCCATGAAGTCAACTTTGATGTTTTG
    GTATCTCCAAAAGCAGCATTGAACGATGAGTACCTCAAACAAAAATTAGCAGAAGTTGAA
    GCTGCTAAGAACAAGGTGGTCTATAACTTTGCTTCACCAGAAGTAAAAGAAGCTTTCTTG
    AAAGCAATTGAAGCGGCCGAACAAGTGTTGAAAGACCATGAAATTAGCACCCAAGATCAA
    GTCAATGACCGACTTAATAAATTGACAGAAGCTCATAAAGCTCTGAATGGTCAAGAGAAA
    TTTAAGGAAGAAAAGACAGAGCTTGATCGTTTAACAGGTGAGGTTCAAGAACTCTTGGCT
    GCCAAACCAAACCATCCTTCAGGTTCTGCCCTAGCTCCGCTTCTTGAGAAAAACAAGGCC
    TTGGTTGAAAAAGTAGATTTGAGTCCAGAAGAGCTTGCAACAGCGAAACAGAGTCTAAAA
    GATCTGGTTGCTTTATTGAAAGAAGACAAGCCAGCAGTCTTTTCTGATAGTAAAACAGGT
    GTTGAAGTACACTTCTCAAATAAAGAGAAGACTGTCATCAAGGGTTTGAAAGTAGAGCGT
    GTTCAAGCAAGTGCTGAAGAGAAGAAATACTTTGCTGGAGAAGATGCTCATGTCTTTGAA
    ATAGAAGGTTTGGATGAAAAAGGTCAAGATGTTGATCTCTCTTATGCTTCTATTGTGAAA
    ATTCCAATTGAAAAAGATAAGAAAGTTAAGAAAGTATTTTTCTTACCTGAAGGCAAAGAG
    GCAGTAGAATTGGCTTTTGAACAAACGGATAGTCATGTTATCTTTACAGCACCTCACTTT
    ACTCATTATGCCTTTGTTTATGAATCTGCTGAAAAACCACAACCTGCTAAACCAGCACCA
    CAAAACACAGTCCTTCCAAAACCTACTTATCAACCGGCTTCTGATCAACAAAAGGCTCCT
    AAATTGGAAGTTCAAGAGGAAAAGGTTGCCTTTCATCGTCAAGAGCATGAAAATGCTGAG
    ATGCTAGTTGGGGAACAACGAGTCATCATACAGGGACGAGATGGACTGTTAAGACATGTC
    TTTGAAGTTGATGAAAACGGTCAGCGTCGTCTTCGTTCAACAGAAGTCATCCAAGAAGCG
    ATTCCAGAAATTGTTGAAATTGGAACAAAAGTAAAAACAGTACCAGCAGTAGTAGCTATA
    CAGGAAAAACCAGCTCAAAATACAGCAGTTAAATCAGAAGAAGCAAGCAAACAATTGCCA
    AATACAGGAACAGCTGATGCTAATGAAGCCCTAATAGCAGGTTTAGCCAGCCTCGGTCTT
    GCTAGTTTAGCCTTGACCTTGAGACGGAAAAGAGAAGATAAAGATTAA
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    4908

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: A66_00463 [new locus tag: A66_RS02325 ]
  • symbol: A66_00463
  • description: Endo-beta-N-acetylglucosaminidase
  • length: 1635
  • theoretical pI: 4.87237
  • theoretical MW: 180364
  • GRAVY: -0.615352

⊟Function[edit | edit source]

  • reaction:
    EC 3.2.1.96?  ExPASy
    Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -(Man(GlcNAc)2)Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact
  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 25.2)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Glyco_hydro_tim (CL0058) Glyco_hydro_85; Glycosyl hydrolase family 85 (PF03644; HMM-score: 245.4)
    and 5 more
    E-set (CL0159) Big_3; Bacterial Ig-like domain (group 3) (PF07523; HMM-score: 120.5)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 47)
    B_GA (CL0598) FIVAR; FIVAR domain (PF07554; HMM-score: 25.4)
    GBD (CL0202) F5_F8_type_C; F5/8 type C domain (PF00754; HMM-score: 24.7)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 23.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.97
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.260844
    • TAT(Tat/SPI): 0.010931
    • LIPO(Sec/SPII): 0.016383
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CRI61174 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MIGAVLFAGPALAEETAVPENSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVATASETASPASNEAATTETAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAEEANKTEKEVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGVREDDAINRGSVVLASRRTGHLVNEKASKEAKVQTLSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFALSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGATITVYDNPNSQIPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLQVQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKNYLVGDSLDLSEGCFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHEISTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVAIQEKPAQNTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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