PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 16-MAY-2019

⊟Summary

• organism: Streptococcus pneumoniae EF3030
• locus tag: EF3030_04180 [new locus tag: EF3030_RS04180 ]
• pan locus tag^?: PNEUPAN001836000
• symbol: EF3030_04180
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: EF3030_04180 [new locus tag: EF3030_RS04180 ]
• symbol: EF3030_04180
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 787292..787825
• length: 534
• essential: unknown

⊟Accession numbers

• Location: CP035897 (787292..787825) NCBI
• BioCyc: see EF3030_RS04180
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_0775 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  
  TTGTATCATGAAACGGAGCTTGCGACAAGAAAGGGAAATTTCTCTTTTTTTAAGATTTTT
  TTAAAGAAACAGAGTATAATAAATCATAATCAAAGGAGAGAATGTATGTCTAACTATCGT
  AGAACTTCAAAACCAAAAACAGAACACATCAAAAAAGGCTTTACAGTCTTTCAAAAAACC
  GTTGCTACAATCGCTAGTATCCTTGGCTTGATTACCGCAAGTATCACGATTATGAACGCC
  TTGGATAATAACAAAAATATTAAAAAAGAACCTACGACAAGCCAGACGACAACCATTGTC
  AAAGAAATCCAAAAGGAATCCCCTAAGGAAAACACCAGTCCAACTAAAGAGACTAACACT
  AGTCAAGAAAAAACACAGCAAGAGGAAACACCAAAATCTAGCGTCAAGGAAGAGAAAAAA
  GAAGATCAGAAAACAGCAACTCAGGACTCTTCTACTCCTGCTTCAAGTAAACCTGCTACT
  GAAAACGAAAAACAGTCCAATGCGCCAACTTCAGAAAATAAAAGCAATCAATAG
  60
  120
  180
  240
  300
  360
  420
  480
  534
  

⊟Protein

⊟General

• locus tag: EF3030_04180 [new locus tag: EF3030_RS04180 ]
• symbol: EF3030_04180
• description: hypothetical protein
• length: 177
• theoretical pI: 10.2804
• theoretical MW: 20015.2
• GRAVY: -1.2

⊟Function

• TIGRFAM:
  mobilome CxxCx(11)CxxC protein (TIGR04402; HMM-score: 16.7)
  and 3 more
  cobaltochelatase subunit (TIGR02442; EC 6.6.1.2; HMM-score: 12.3)
  pullulanase, extracellular (TIGR02102; HMM-score: 6.7)
  Metabolism Energy metabolism TCA cycle dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex (TIGR01347; EC 2.3.1.61; HMM-score: 6.2)
• TheSEED: data available for D39, Hungary19A-6, TIGR4
• PFAM:
  no clan defined DUF6556; Family of unknown function (DUF6556) (PF20193; HMM-score: 103.3)
  and 12 more
  Pep1_7; Elicitor peptide 1-7 (PF17232; HMM-score: 20.2)
  MotA_ExbB; MotA/TolQ/ExbB proton channel family (PF01618; HMM-score: 16.2)
  SGNH_hydrolase (CL0264) Lipase_GDSL_3; GDSL-like Lipase/Acylhydrolase family (PF14606; HMM-score: 14.4)
  MFS (CL0015) BT1; BT1 family (PF03092; HMM-score: 13.2)
  HTH (CL0123) DUF2551; Protein of unknown function (DUF2551) (PF10826; HMM-score: 12.7)
  no clan defined Serinc; Serine incorporator (Serinc) (PF03348; HMM-score: 10.6)
  DUF5427; Family of unknown function (DUF5427) (PF10310; HMM-score: 9.5)
  DMT (CL0184) Zip; ZIP Zinc transporter (PF02535; HMM-score: 9.2)
  no clan defined CIS_TMP; Contractile injection system tape measure protein (PF19268; HMM-score: 8.5)
  DDHD; DDHD domain (PF02862; HMM-score: 7.8)
  GPCR_A (CL0192) SID-1_RNA_chan; dsRNA-gated channel SID-1 (PF13965; HMM-score: 6.9)
  no clan defined CobT; Cobalamin biosynthesis protein CobT (PF06213; HMM-score: 5.9)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helix: 1
• DeepLocPro: Extracellular
  • Cytoplasmic Score: 0.1226
  • Cytoplasmic Membrane Score: 0.2755
  • Cell wall & surface Score: 0.2703
  • Extracellular Score: 0.3316
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.019954
  • TAT(Tat/SPI): 0.002648
  • LIPO(Sec/SPII): 0.004645
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: QBF68768 NCBI
• UniProt:

⊟Protein sequence

• MYHETELATRKGNFSFFKIFLKKQSIINHNQRRECMSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMNALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKEEKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V: SPV_0775 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications