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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 49619
  • locus tag: EL263_RS03185 [old locus tag: SPAT_0591 ]
  • pan locus tag?: PNEUPAN001574000
  • symbol: EL263_RS03185
  • pan gene symbol?: prtA
  • synonym:
  • product: S8 family serine peptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL263_RS03185 [old locus tag: SPAT_0591 ]
  • symbol: EL263_RS03185
  • product: S8 family serine peptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 590823..597257
  • length: 6435
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018938 (590823..597257) NCBI
  • BioCyc: EL263_RS03185 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0558 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
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    3541
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    3841
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    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
    5761
    5821
    5881
    5941
    6001
    6061
    6121
    6181
    6241
    6301
    6361
    6421
    ATGAAAAAAAGTACAGTATTGTCATTAACTACAGCTGCAGTTATTTTAGCAGCCTATGCC
    CCTAATGAGGTAGTCTTAGCAGACACATCTAGCTCTGAAGATGCTTTAAGCATCTCTGAT
    AAAGAAAAAGTAGTAGTAGATAAGGAAACAGAAAATAAAGAGAAACATAAAGATATTCAT
    AATGCTATAGAAACTTCAAAGGATACTGAAGAAAAGAAAACAACAATTATTGAGGAAAAA
    GAAGTTGTTAGTAAAAATCCTGTGATAGACACTAAAACTAGCAATGAAGAAGCAAGAATC
    AAAGAAGATTCCAATCAATCCCAAGGAGATAATGCACACTCGTCTGCAAATAAAGGCACA
    GAAAATCCGAAAAAAGAAGATAGACTTGTCTATATTGCTGAATTTAAAGATAAAGAATCT
    GGAGAAAAAGCAATCAAGGGACTATCAAATCTTAAGAATACAAAAGTTTTATATACTTAT
    GATAGAATTTTTAACGGTAGTGCCATAGAAACAACTCCAGATAACTTGGACAAAATTAAA
    CAAATAGAAGGTATTTCATCGGTTGAAAGGGCACAAAAAGTCCAACCCATGATGAATCAT
    GCCAGAAAGGAAATTGGAGTTGAGGAAGCTATTGATTACCTAAAGTCTATCAATGCTCCA
    TTTGGGAAAAATTTTGATGGTAGAGGTATGGTCATTTCAAATATCGATACTGGAACAGAT
    TATAGGCATAAGGCTATGAGAATCGATGATGATGCCAAAGCCTCAATGAGATTTAAAAAA
    GAAGACTTAAAAGGAACTGATAAAAATTATTGGTTGAGTGATAAAATCCCTCATGCGTTC
    AATTATTATAATGGTGGCAAAATCACTGTAGAAAAATATGATGATGGAAGGGATTATTTT
    GACCCACATGGGATGCATATTGCAGGGATTCTTGCTGGAAATGATACTGAACAAGATATC
    AAAAACTTTAACGGCATAGATGGAATTGCACCTAATGCACAAATTTTCTCTTACAAAATG
    TATTCTGACGCAGGATCTGGGTTTGCGGGTGATGAAACAATGTTTCATGCTATTGAAGAT
    TCTATCAAACACAACGTTGATGTTGTTTCGGTATCATCTGGTTTTACAGGAACAGGTCTT
    GTAGGTGAGAAATATTGGCAAGCTATTAGGGCATTAAGAAAAGCAGGCATTCCAATGGTT
    GTCGCTACGGGTAACTATGCGACTTCTGCTTCAAGTTCTTCATGGGATTTAGTAGCAAAT
    AATCATCTGAAAATGACCGACACTGGAAATGTAACACGAACTGCAGCACATGAGGATGCG
    ATAGCGGTCGCTTCTGCTAAAAATCAAACAGTTGAGTTTGATAAAGTTAACATAGGTGGA
    GAAAGTTTTAAATACAGAAATATAGGGGCCTTTTTCGATAAGAATAAAATCACAACAAAT
    GAAGATGGAACAAAAGCTCCTAGTAAATTAAAATTTGTATATATAGGCAAGGGGCAAGAC
    CAAGATTTGATAGGTTTGGATCTTAGGGGCAAAATTGCAGTAATGGATAGAATTTATACA
    AAGGATTTAAAAAATGCTTTTAAAAAAGCTATGGATAAGGGTGCACGCGCCATTATGGTT
    GTAAATACTGTAAATTACTACAATAGAGATAATTGGACAGAGCTTCCAGCTATGGGATAT
    GAAGCGGATGAAGGTACTAAAAGTCAAGTGTTTTCAATTTCAGGAGATGATGGTGTAAAG
    CTATGGAACATGATTAATCCTAATAAAAAAACTGAAGTCAAAAGAAATAATAAAGAAGAT
    TTTAAAGATAAATTGGAGCAATACTATCCAATTGATATGGAAAGTTTTAATTCCAACAAA
    CCGAATGTAGGTGACGAAAAAGAGATTGACTTTAAGTTTGCACCTGACACAGACAAAGAA
    CTCTATAAAGAAGATATCATCGTTCCAGCAGGATCTACATCTTGGGGGCCAAGAATAGAT
    TTACTTTTAAAACCCGATGTTTCAGCACCTGGTAAAAATATTAAATCCACGCTTAATGTT
    ATTAATGGCAAATCAACTTATGGCTATATGTCAGGAACTAGTATGGCGACTCCAATCGTG
    GCAGCTTCTACTGTTTTGATTAGACCGAAATTAAAGGAAATGCTTGAAAGACCTGTATTG
    AAAAATCTTAAGGGAGATGACAAAATAGATCTTACAAGTCTTACAAAAATTGCCCTACAA
    AATACTGCGCGACCTATGATGGATGCAACTTCTTGGAAAGAAAAAAGTCAATACTTTGCA
    TCACCTAGACAACAGGGAGCAGGCCTAATTAATGTGGCCAATGCTTTGAGAAATGAAGTT
    GTAGCAACTTTCAAAAACACTGATTCTAAAGGTTTGGTAAACTCATATGGTTCCATTTCT
    CTTAAAGAAATAAAAGGTGATAAAAAATACTTTACAATCAAGCTTCACAATACATCAAAC
    AGACCTTTGACTTTTAAAGTTTCAGCATCAGCGATAACTACAGATTCTCTAACTGACAGA
    TTAAAACTTGATGAAACATATAAAGATGAAAAATCTCCAGATGGTAAGCAAATTGTTCCA
    GAAATTCACCCAGAAAAAGTCAAAGGAGCAAATATCACATTTGAGCATGATACTTTCACT
    ATAGGCGCAAATTCTAGCTTTGATTTGAATGCGGTTATAAATGTTGGAGAGGCTAAAAAC
    AAAAATAAATTTGTAGAATCATTTATTCATTTTGAGTCAGTGGAAGAAATGGAAGCTCTA
    AACTCCAACGGGAAGAAAATAAACTTCCAACCTTCTTTGTCGATGCCTCTAATGGGATTT
    GCTGGGAATTGGAACCACGAACCAATCCTTGATAAATGGGCTTGGGAAGAAGGGTCAAGA
    TCAAAAACACTGGGAGGTTATGATGATGATGGTAAACCGAAAATTCCAGGAACCTTAAAT
    AAGGGAATTGGTGGAGAACATGGTATAGATAAATTTAATCCAGCAGGAGTTATACAAAAT
    AGAAAAGATAAAAATACAACATCCCTGGATCAAAATCCAGAATTATTTGCTTTCAATAAC
    GAGGGGATCAACGCTCCATCATCAAGTGGTTCTAAGATTGCTAACATTTATCCTTTAGAT
    TCAAATGGAAATCCTCAAGATGCTCAACTTGAAAGAGGATTAACACCTTCTCCACTTGTA
    TTAAGAAGTGCAGAAGAAGGATTGATTTCAATAGTAAATACAAATAAAGAGGGAGAAAAT
    CAAAGAGACTTAAAAGTCATTTCGAGAGAACACTTTATTAGAGGAATTTTAAATTCTAAA
    AGCAATGATGCAAAGGGAATCAAATCATCTAAACTAAAAGTTTGGGGTGACTTGAAGTGG
    GATGGACTCATCTATAATCCTAGAGGTAGAGAAGAAAATGCACCAGAAAGTAAGGATAAT
    CAAGATCCTGCTACTAAGATAAGAGGTCAATTTGAACCGATTGCGGAAGGTCAATATTTC
    TATAAATTTAAATATAGATTAACTAAAGATTACCCATGGCAGGTTTCCTATATTCCTGTA
    AAAATTGATAACACCGCCCCTAAGATTGTTTCGGTTGATTTTTCAAATCCTGAAAAAATT
    AAGTTGATTACAAAGGATACTTATCATAAGGTAAAAGATCAGTATAAGAATGAAACGCTA
    TTTGCGAGAGATCAAAAAGAACATCCTGAAAAATTTGACGAGATTGCGAACGAAGTTTGG
    TATGCTGGCGCCGCTCTTGTTAATGAAGATGGAGAGGTTGAAAAAAATCTTGAAGTAACT
    TACGCAGGTGAGGGTCAAGGAAGAAATAGAAAACTTGACAAAGACGGAAATACCATTTAT
    GAAATTAAAGGTGCGGGAGATTTAAGGGGAAAAATCATTGAAGTCATTGCATTAGATGGT
    TCTAGCAATTTCACAAAGATTCATAGAATTAAATTTGCTAATCAGGCTGATGAAAAGGGG
    ATGATTTCCTATTATCTAGTAGATCCTGATCAAGATTCATCTAAATATCAAAAGCTTGGC
    GAGATTGCAGAATCTAAATTTAAAAATTTAGGAAATGGAAAAGAGGGTAGTCTAAAAAAA
    GATACAACTGGGGTAGAACATCATCATCAAGAAAATGAAGAGTCTATTAAAGAAAAATCT
    AGTTTTACTATTGATAGAAATATTTCAACAATTAGAGACTTTGAAAATAAAGACTTAAAG
    AAACTCATTAAAAAGAAATTTAGAGAAGTTGAGGACTTTACAAGTGAAACTGGTAAGAGG
    AAACAAGAATACGATTATAAATACGATGATAAGGGAAATATCATTGCTTATGACGATGAT
    AGTGCCTTACAATATGAAACTGAAAAGCTTGATGAAATAAAATCAAAGATTTATGGTGTT
    CTAAGCCCGTCTAAAGATGGACACTTTGAAATTCTTGGAAAGATAAGCAATGTTTCTAAA
    AATGCCAAGGTATATTATGGAAATAACTATAAATTTATAGAAATCAAAGCGACTAAGTAT
    GACTCACATTCAAAAACGATGACATTTGATTTATACGCTAATATTAATGATATTGTGGAT
    GGATTAGCTTTTGCTGGAGATATGCGGTTTTTTGTTAAAGATGATGATCGAATAAAAGCT
    GAAATTAAAATTAGAATGCCTGAAAAAAATAAGGAAACTAAAGCAGAATATCCCTATGTA
    TCAAGTTATGGGAATGTAATCGAATTAGGAGAAGGAGATCTTTCAAAGAACAAACCAGAC
    AATTTAACTAAAATGGAATCTGGTAAAATCTATTCTGATTCAGAAAAACAACAATATCTG
    TTAAAGGATAACATCATTCTAAGAAAAGGCTATGCACTAAAAGTGACTACCTATAATCCT
    GGAAAAACGGATATGTTAGAAGGGAATGGAGTCTATAGCAAGGAAGATATAGCAAAAATA
    CAAAAGGCCAATCCTAATCTAAGAGTCCTTTCAGAAACAACAATTTATGCTGATAGTAGA
    AATGTTGAAGATGGAAGAAGTACCCAAGCTGTATTAATGTCGGCTTTGGACGGCTTTAAC
    ATTATAAGGTATCAAGTGTTTACATTTAAAATGAACGATAAAGGGGAAGCTATCGATAAA
    GACGGAAATCTTGTGACAGATTCTTCTAAACTTGTATTATTTGGTAAGGATGATAAAGAA
    TACACTGGAGAGGATAAGTCCAATGTAGAAGCTATAAAAGAAGATGGCTCCATGTTATTT
    ATTGATACCAAACCAGTAAACCTTTCAATGGATAAGAACTACTTTAATCCATCTAAATCT
    AATAAAATTTATGTACGAAATCCAGAATTTTATTTAAGAGGTAAGATTTCTGATAAGGGT
    GGTTTTAACTGGGAATTGAGAGTTAATGAATCGGTTGTAGATAATTATTTAATCTACGGA
    GATTTACACATTGATAACACTAGAGATTTTAATATTAAGCTGAATGTTAAAGACGGTGAC
    ATCATGGACTGGGGAATGAAAGACTATAAAGCAAACGGATTTCCAGATAAGGTAACAGAT
    ATGGATGGAAATGTTTATCTTCAAACTGGCTATAGCGATTTGAATGCTAAAGCAGTTGGA
    GTCCACTATCAGTTTTTATATGATAATGTTAAACCTGAAGTAAACATTGATCCTAAGGGA
    AATACTAGTATCGAATATGCTGATGGAAAATCTGTAGTCTTTAACATCAATGATAAAAGA
    AATAATGGATTCGATGGTGAGATTCAAGAACAACATATTTATGTAAATGGAAAAGAATAT
    ACATCATTTGATTATATTAAACAAATAATAGACAAGACACTAAACATTAAGATTGTTGTA
    AAAGATTTTGCAAGAAATACAACCGTAAAAGAATTCATTTTAAATAAAGATACGGGAGAG
    GTAAGTGAATTAAAACCTCATAGGGTAACTGTGACCATTCAAAATGGAAAAGAAATGAGT
    TCAACGATAGTGTCGGAAGAAGATTTTATTTTACCTGTTTATAAGGGTGAATTAGAAAAA
    GGATACCAATTTGATGGTTGGGAAATTTCTGGTTTCGAAGGTAAAAAAGACGCTGGCTAT
    GTTATTAATCTATCAAAAGATACCTTTATAAAACCTGTATTCAAGAAAATAGAGGAGAAA
    AAGGAGGAAGAAAATAAACCTACTTTTGATGTATCGAAAAAGAAAGATAACCCACAAGTA
    AACCATAGTCAATTAAATGAAAGTCACAGAAAAGAGGATTTACAAAGAGAAGATCATTCA
    CAAAAATCTGATTCAACTAAGGATGTTACAGCTACAGTTCTTGATAAAAACAATATCAGT
    AGTAAATCAACTACTAACAATCCTAATAAGTTGCCAAAAACTGGAACAGCAAGCGGAGCC
    CAGACACTATTAGCTGCCGGAATAATGTTTATAGTAGGAATTTTTCTTGGATTGAAGAAA
    AAAAATCAAGATTAA
    60
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    6300
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    6420
    6435

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL263_RS03185 [old locus tag: SPAT_0591 ]
  • symbol: EL263_RS03185
  • description: S8 family serine peptidase
  • length: 2144
  • theoretical pI: 6.36679
  • theoretical MW: 240745
  • GRAVY: -0.738433

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 63.6)
    Genetic information processing Protein fate Protein modification and repair type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 63.6)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 24)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Peptidase_S8; Subtilase family (PF00082; HMM-score: 123.7)
    E-set (CL0159) fn3_5; Fn3-like domain (PF06280; HMM-score: 109.5)
    and 4 more
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 27.2)
    Leu-IlvD (CL0364) PA; PA domain (PF02225; HMM-score: 23.9)
    PPP-I (CL0570) Inhibitor_I9; Peptidase inhibitor I9 (PF05922; HMM-score: 20.7)
    Concanavalin (CL0004) Gal-bind_lectin; Galactoside-binding lectin (PF00337; HMM-score: 11.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helix: 1
  • SignalP: Signal peptide SP(Sec/SPI) length 27 aa
    • SP(Sec/SPI): 0.962371
    • TAT(Tat/SPI): 0.003345
    • LIPO(Sec/SPII): 0.026751
    • Cleavage Site: CS pos: 27-28. VLA-DT. Pr: 0.8964
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_050268398 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKVVVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEARIKEDSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTYDRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNEGINAPSSSGSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSFTIDRNISTIRDFENKDLKKLIKKKFREVEDFTSETGKRKQEYDYKYDDKGNIIAYDDDSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAEIKIRMPEKNKETKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDGEIQEQHIYVNGKEYTSFDYIKQIIDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGLKKKNQD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

G Bethe, R Nau, A Wellmer, R Hakenbeck, R R Reinert, H P Heinz, G Zysk
The cell wall-associated serine protease PrtA: a highly conserved virulence factor of Streptococcus pneumoniae.
FEMS Microbiol Lett: 2001, 205(1);99-104
[PubMed:11728722] [WorldCat.org] [DOI] (P p)Shaper Mirza, Landon Wilson, William H Benjamin, Jan Novak, Stephen Barnes, Susan K Hollingshead, David E Briles
Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.
Infect Immun: 2011, 79(6);2440-50
[PubMed:21422179] [WorldCat.org] [DOI] (I p)Sacha F de Stoppelaar, Hester J Bootsma, Aldert Zomer, Joris J T H Roelofs, Peter W M Hermans, Cornelis van 't Veer, Tom van der Poll
Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.
PLoS One: 2013, 8(11);e80062
[PubMed:24244609] [WorldCat.org] [DOI] (I e)

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