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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 07-FEB-2021
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae AP200
- locus tag: SPAP_RS03120 [old locus tag: SPAP_0630 ]
- pan locus tag?: PNEUPAN001574000
- symbol: SPAP_RS03120
- pan gene symbol?: prtA
- synonym:
- product: S8 family serine peptidase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS, pseudogene
- locus tag: SPAP_RS03120 [old locus tag: SPAP_0630 ]
- symbol: SPAP_RS03120
- product: S8 family serine peptidase
- replicon: chromosome
- strand: +
- coordinates: 593182..599614
- length: 6433
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_014494 (593182..599614) NCBI
- BioCyc: SPAP_RS03120 BioCyc
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0558 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1021
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1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
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5641
5701
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5941
6001
6061
6121
6181
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6421ATGAAAAAAAGTACAGTATTGTCATTAACCACAGCTGCAGTTATTTTAGCAGCCTATGCC
CCTCATGAGGTAGTCTTAGCAGACACATCTAACTCTGAAGATGCTTTAAGCATCTCTGAT
AAAGAAAAAGTAGTAGTAGATAAGGAAACAGAAAATAAAGAGAAACATAAAGATATTCAT
AATGCTATAGAAACTTCAAAGGATACTGAAGAAAAGAAAACAACAATTATTGAGGAAAAA
GAAGTTGTTAGTAAAAATACCTGTGATAGACAATAACACTAGCAATGAAGAAGCAAGAAT
CAAAGAAGATTCCAATCAATCTCAAGGAGATAATGCACACTCGTCTGCAAATAAAAACAC
AGAAAATCCCAAAAAAGAAGATAAAGTTGTCTATATTGCTGAATTTAAAGATAAAGAATC
TGGAGAAAAAGCAATCAAGCAACTATCCAGTCTTAAGAATACAAAAGTTTTATATACTTA
TGATAGAATTTTTAACGGTAGTGCTATAGAAACAACTCCAGATAACTTGGACAAAATTAA
ACAAATAGAAGGTATTTCATCGGTTGAAAGGGCACAAAAAGTCCAACCCATGATGAATCA
TGCCAGAAAGGAAATTGGAGTTGAGGAAGCTATTGATTACCTAAAGTCTATCAATGCTCC
GTTTGGGAAAAATTTTGATGGTAGAGGTATGGTCATTTCAAATATCGATACTGGAACAGA
TTATAGACATAAGGCTATGAGAATCGATGATGATGCCAAAGCCTCAATGAGATTTAAAAA
AGAAGACTTAAAAGGTACTGATAAAAATTATTGGTTGAGTGATAAAATCCCTCATGCGTT
CAATTATTATAATGGTGGCAAAATCACTGTAGAAAAATATGATGATGGAAGGGATTATTT
TGACCCACATGGGATGCATATTGCAGGGATTCTTGCTGGAAATGATACTGAACAAGATAT
CAAAAACTTTAACGGCATAGATGGAATTGCACCTAATGCACAAATTTTCTCTTACAAAAT
GTATTCTGACGCAGGATCTGGGTTTGCGGGTGATGAAACAATGTTTCATGCTATTGAAGA
TTCTATCAAACACAACGTTGATGTTGTTTCGGTATCATCTGGTTTTACAGGAACAGGTCT
TGTAGGTGAGAAATATTGGCAAGCTATTAGGGCATTAAGAAAAGCAGGCATTCCAATGGT
TGTCGCTACGGGTAACTATGCGACTTCTGCTTCAAGTTCTTCATGGGATTTAGTAGCAAA
TAATCATCTGAAAATGACCGACACTGGAAATGTAACACGAACTGCAGCACATGAGGATGC
GATAGCGGTCGCTTCTGCTAAAAATCAAACAGTTGAGTTTGATAAAGTTAACATAGGTGG
AGAAAGTTTTAAATACAGAAATATAGGGGCCTTTTTCGATAAGAATAAAATCACAACAAA
TGAAGATGGAACAAAAGCTCCTAGTAAATTAAAATTTGTATATATAGGCAAGGGGCAAGA
CCAAGATTTGATAGGTTTGGATCTTAGGGGCAAAATTGCAGTAATGGATAGAATTTATAC
AAAGGATTTAAAAAATGCTTTTAAAAAAGCTATGGATAAGGGTGCACGCGCCATTATGGT
TGTAAATACTGTAAATTACTACAATAGAGATAATTGGACAGAGCTTCCAGCTATGGGATA
TGAAGCGGATGAAGGTACTAAAAGTCAAGTGTTTTCAATTTCAGGAGATGATGGTGTAAA
GCTATGGAACATGATTAATCCTGATAAAAAAACTGAAGTCAAAAGAAATAATAAAGAAGA
TTTTAAAGATAAATTGGAGCAATACTATCCAATTGATATGGAAAGTTTTAATTCCAACAA
ACCGAATGTAGGTGACGAAAAAGAGATTGACTTTAAGTTTGCACCTGACACAGACAAAGA
ACTCTATAAAGAAGATATCATCGTTCCAGCAGGATCTACATCTTGGGGGCCAAGAATAGA
TTTACTTTTAAAACCCGATGTTTCAGCACCTGGTAAAAATATTAAATCCACGCTTAATGT
TATTAATGGCAAATCAACTTATGGCTATATGTCAGGAACTAGTATGGCGACTCCAATCGT
GGCAGCTTCTACTGTTTTGATTAGACCGAAATTAAAGGAAATGCTTGAAAGACCTGTATT
GAAAAATCTTACGGGAGATGACAAAATAGATCTTACAAGTCTTACAAAAATTGCCCTACA
AAATACTGCGCGACCTATGATGGATGCAACTTCTTGGAAAGAAAAAAGTCAATACTTTGC
ATCACCTAGACAACAGGGAGCAGGCCTAATTAATGTGGCCAATGCTTTGAGAAATGAAGT
TGTAGCAACTTTCAAAAACACTGATTCTAAAGGTTTGGTAAACTCATATGGTTCCATTTC
TCTTAAAGAAATAAAAGGTGATAAAAAATACTTTACAATCAAGCTTCACAATACATCAAA
CAGACCTTTGACTTTTAAAGTTTCAGCATCAGCGATAACTACAGATTCTCTAACTGACAG
ATTAAAACTTGATGAAACATATAAAGATGAAAAATCTCCAGATGGTAAGCAAATTGTTCC
AGAAATTCACCCAGAAAAAGTCAAAGGAGCAAATATCACATTTGAGCATGATACTTTCAC
TATAGGCGCAAATTCTAGCTTTGATTTGAATGCGGTTATAAATGTTGGAGAGGCCAAAAA
CAAAAATAAATTTGTAGAATCATTTATTCATTTTGAGTCAGTGGAAGAAATGGAAGCTCT
AAACTCCAACGGGAAGAAAATAAACTTCCAACCTTCTTTGTCGATGCCTCTAATGGGATT
TGCTGGGAATTGGAACCACGAACCAATCCTTGATAAATGGGCTTGGGAAGAAGGGTCAAG
ATCAAAAACACTGGGAGGTTATGATGATGATGGTAAACCGAAAATTCCAGGAACCTTAAA
TAAGGGAATTGGTGGAGAACATGGTATAGATAAATTTAATCCAGCAGGAGTTATACAAAA
TAGAAAAGATAAAAATACAACATCCCTGGATCAAAATCCAGAATTATTTGCTTTCAATAA
CGAAGGGATCAACGCTCCATCATCAAGTGGTTCTAAGATTGCTAACATTTATCCTTTAGA
TTCAAATGGAAATCCTCAAGATGCTCAACTTGAAAGAGGATTAACACCTTCTCCACTTGT
ATTAAGAAGTGCAGAAGAAGGATTGATTTCAATAGTAAATACAAATAAAGAGGGAGAAAA
TCAAAGAGACTTAAAAGTCATTTCGAGAGAACACTTTATTAGAGGAATTTTAAATTCTAA
AAGCAATGATGCAAAGGGAATCAAATCATCTAAACTAAAAGTTTGGGGTGACTTGAAGTG
GGATGGACTCATCTATAATCCTAGAGGTAGAGAAGAAAATGCACCAGAAAGTAAGGATAA
TCAAGATCCTGCTACTAAGATAAGAGGTCAATTTGAACCGATTGCGGAAGGTCAATATTT
CTATAAATTTAAATATAGATTAACTAAAGATTACCCATGGCAGGTTTCCTATATTCCTGT
AAAAATTGATAACACCGCCCCTAAGATTGTTTCGGTTGATTTTTCAAATCCTGAAAAAAT
TAAGTTGATTACAAAGGATACTTATCATAAGGTAAAAGATCAGTATAAGAATGAAACGCT
ATTTGCGAGAGATCAAAAAGAACATCCTGAAAAATTTGACGAGATTGCGAACGAAGTTTG
GTATGCTGGCGCCGCTCTTGTTAATGAAGATGGAGAGGTTGAAAAAAATCTTGAAGTAAC
TTACGCAGGTGAGGGTCAAGGAAGAAATAGAAAACTTGACAAAGACGGAAATACCATTTA
TGAAATTAAAGGTGCGGGAGATTTAAGGGGAAAAATCATTGAAGTCATTGCATTAGATGG
TTCTAGCAATTTCACAAAGATTCATAGAATTAAATTTGCTAATCAGGCTGATGAAAAGGG
GATGATTTCCTATTATCTAGTAGATCCTGATCAAGATTCATCTAAATATCAAAAGCTTGG
CGAGATTGCAGAATCTAAATTTAAAAATTTAGGAAATGGAAAAGAGGGTAGTCTAAAAAA
AGATACAACTGGGGTAGAACATCATCATCAAGAAAATGAAGAGTCTATTAAAGAAAAATC
TAGTTTTACTATTGATAGAAATATTTCAACAATTAGAGACTTTGAAAATAAAGACCTAAA
GAAACTCATTAAAAAGAAATATAAGGAAGAAGACGACTTTGTAACTGGTGGAAAAAGAAC
AGTAGAACTTGATTATAAATATGACGATAAAGGAAATATAACTGCCTATGAAGATGAAAG
TGCTCTAGAATATGAAACTGAAAAATTTGACGAAATAAAATCAAAAATTTATGGTGTTCT
AAGCCCATCTAAAGATGGACACTTTGAAATTCTTGGAAAGATAAGCAATGTTTCTAAAAA
TGCCAAGGTATATTATGGAAATAACTATAAATTTATAGAAATCAAAGCGACTAAGTATGA
CTCACATTCAAAAACGATGATATTTGATTTATACGCTAATATTAATGATATTGTAGATGG
ATTAGCTTTTGCTGGAGATATGAGATTATTTGTTAAAGATGACAATCAAATAAAAGCTGA
AACTAAAATTAGAATGCCTGAAAAAAATAAGGAAACTAAAGCAGAATATCCGTATGTATC
AAGTTATGGGAATGTAATCGAATTAGGAGAAGGAGACCTTTCAAAAAACAAACCAGACAA
TTTAACTAAAATGGAATCTGGTAAAATCTATTCTGATTCAGAAAAACAACAATATCTGTT
AAAGGATAACATCATTCTAAGAAAAGGCTATGCACTAAAAGTGACTACCTATAATCCTGG
AAAAACGGATATGTTAGAAGGAAATGGAGTCTATAGCAAGGAAGATATAGCAAAAATACA
AAAGGCCAATCCTAATCTAAGAGTCCTTTCAGAAACAACAATTTATGCTGATAGTAGAAA
TGTTGAAGATGGAAGAAGTACCCAAGCTGTATTAATGTCGGCTTTGGACGGCTTTAACAT
TATAAGGTATCAAGTGTTTACATTTAAAATGAACGATAAAGGGGAAGCTATCGATAAAGA
CGGAAATCTTGTGACAGATTCTTCTAAACTTGTATTATTTGGTAAGGATGATAAAGAATA
CACTGGAGAGGATAAGTCCAATGTAGAAGCTATAAAAGAAGATGGCTCCATGTTATTTAT
TGATACCAAACCAGTAAACCTTTCAATGGATAAGAACTACTTTAATCCATCTAAATTTAA
TAAAATTTATGTACGAAATCCAGAATTTTATTTAAGAGGTAAGATTTCTGATAAGGGTGG
TTTTAACTGGGAATTGAGAGTTAATGAATCGGTTGTAGATAATTATTTAATCTACGGAGA
TTTACACATTGATAACACTAGAGATTTTAATATTAAGCTGAATGTTAAAGACGGTGACAT
CATGGACTGGGGAATGAAAGACTATAAAGCAAACGGATTTCCAGATAAGGTAACAGATAT
GGATGGAAATGTTTATCTTCAAACTGGCTATAGTGATTTGAATGCTAAAGCAGTTGGAGT
CCACTATCAGTTTTTATATGATAATGTTAAACCCGAAGTAAACATTGATCCTAAGGGAAA
TACTAGTATCGAATATGCTGATGGAAAATCTGTAGTCTTTAACATCAATGATAAAAGAAA
TAATGGATTCGATGGTGAGATTCAAGAACAACATATTTATATAAATGGAAAAGAATATAC
ATCATTTGATGATATTAAACAAATAATAGACAAGACACTAAACATTAAGATTGTTGTAAA
AGATTTTGCAAGAAATACAACCGTAAAAGAATTCATTTTAAATAAAGATACGGGAGAGGT
AAGTGAATTAAAACCTCATAGGGTAACTGTGACCATTCAAAATGGAAAAGAAATGAGTTC
AACGATAGTGTCGGAAGAAGATTTTATTTTACCTGTTTATAAGGGTGAATTAGAAAAAGG
ATACCAATTTGATGGTTGGGAAATTTCTGGTTTCGAAGGTAAAAAAGACGCTGGCTATGT
TATTAATCTATCAAAAGATACCTTTATAAAACCTGTATTCAAGAAAATAGAGGAGAAAAA
GGAGGAAGAAAATAAACCTACTTTTGATGTATCGAAAAAGAAAGATAACCCACAAGTAAA
CCATAGTCAATTAAATGAAAGTCACAGAAAAGAGGATTTACAAAGAGAAGAGCATTCACA
AAAATCTGATTCAACTAAGGATGTTACAGCTACAGTTCTTGATAAAAACAATATCAGTAG
TAAATCAACTACTAACAATCCTAATAAGTTGCCAAAAACTGGAACAGCAAGCGGAGCCCA
GACACTATTAGCTGCCGGAATAATGTTTATAGTAGGAATTTTTCTTGGATTGAAGAAAAA
AAATCAAGATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPAP_RS03120 [old locus tag: SPAP_0630 ]
- symbol: SPAP_RS03120
- description: S8 family serine peptidase
- length:
- theoretical pI:
- theoretical MW:
- GRAVY:
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: see SPAP_0630
- PFAM:
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb:
- SignalP:
- predicted transmembrane helices (TMHMM):
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: see SPAP_0630
- UniProt:
⊟Protein sequence[edit | edit source]
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- data available for TIGR4
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0558 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
G Bethe, R Nau, A Wellmer, R Hakenbeck, R R Reinert, H P Heinz, G Zysk
The cell wall-associated serine protease PrtA: a highly conserved virulence factor of Streptococcus pneumoniae.
FEMS Microbiol Lett: 2001, 205(1);99-104
[PubMed:11728722] [WorldCat.org] [DOI] (P p)Shaper Mirza, Landon Wilson, William H Benjamin, Jan Novak, Stephen Barnes, Susan K Hollingshead, David E Briles
Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.
Infect Immun: 2011, 79(6);2440-50
[PubMed:21422179] [WorldCat.org] [DOI] (I p)Sacha F de Stoppelaar, Hester J Bootsma, Aldert Zomer, Joris J T H Roelofs, Peter W M Hermans, Cornelis van 't Veer, Tom van der Poll
Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.
PLoS One: 2013, 8(11);e80062
[PubMed:24244609] [WorldCat.org] [DOI] (I e)