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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-FEB-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39V
  • locus tag: SPV_RS03005 [old locus tag: SPV_0558 ]
  • pan locus tag?: PNEUPAN001574000
  • symbol: SPV_RS03005
  • pan gene symbol?: prtA
  • synonym:
  • product: S8 family serine peptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPV_RS03005 [old locus tag: SPV_0558 ]
  • symbol: SPV_RS03005
  • product: S8 family serine peptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 570405..576839
  • length: 6435
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
    5761
    5821
    5881
    5941
    6001
    6061
    6121
    6181
    6241
    6301
    6361
    6421
    ATGAAAAAAAGCACAGTATTGTCACTAACTACAGCTGCAGTTATTTTAGCAGCCTATGCC
    CCTAATGAGGTAGTCTTAGCAGACACATCTAGCTCTGAAGATGCTTTAAGCATCTCTGAT
    AAAGAAAAAGTAGTAGTAGATAAGGAAACAGAAAATAAAGAGAAACATAAAGATATTCAT
    AATGCTATAGAAACTTCAAAGGATACTGAAGAAAAGAAAACAACAATTATTGAGGAAAAA
    GAAGTTGTTAGTAAAAATCCTGTAATAGACACTAAAACTAGCAATGAAGAAGCAAAAATC
    AAAGAAGAAAATTCCAATCAATCCCAAGGAGATCATACGGACTCATTTGTGAATAAAAAC
    ACAGAAAATCCCAAAAAAGAAGATAAAGTTGTCTATATTGCTGAATTTAAAGATAAAGAA
    TCTGGAGAAAAAGCAATCAAGGGACTATCAAATCTTAAGAATACAAAAGTTTTATATACT
    TATGATAGAATTTTTAACGGTAGTGCCATAGAAACAACTCCAGATAACTTGGACAAAATT
    AAACAAATAGAAGGTATTTCATCGATTGAAAGGGCACAAAAAGTCCAACCCATGATGAAT
    CATGCCAGAAAGGAAATTGGAGTTGAGGAAGCTATTGATTACCTAAAGTCTATCAATGCT
    CCGTTTGGGAAAAATTTTGATGGTAGAGGTATGGTCATTTCAAATATCGATACTGGAACA
    GATTATAGACATAAGGCTATGAGAATCGATGATGATGCCAAAGCCTCAATGAGATTTAAA
    AAAGAAGACTTAAAAGGAACTGATAAAAATTATTGGTTGAGTGATAAAATCCCTCATGCG
    TTCAATTATTATAATGGTGGCAAAATCACTGTAGAAAAATATGATGATGGAAGGGATTAT
    TTTGACCCACATGGGATGCATATTGCAGGGATTCTTGCTGGAAATGATACTGAACAAGAT
    ATCAAAAACTTTAACGGCATAGATGGAATTGCACCTAATGCACAAATTTTCTCTTACAAA
    ATGTATTCTGACGCAGGATCTGGGTTTGCGGGTGATGAAACAATGTTTCATGCTATTGAA
    GATTCTATCAAACACAACGTTGATGTTGTTTCGGTATCATCTGGTTTTACAGGAACAGGT
    CTTGTAGGTGAGAAATATTGGCAAGCTATTCGGGCATTAAGAAAAGCAGGCATTCCAATG
    GTTGTCGCTACGGGTAACTATGCGACTTCTGCTTCAAGTTCTTCATGGGATTTAGTAGCA
    AATAATCATCTGAAAATGACCGACACTGGAAATGTAACACGAACTGCAGCACATGAGGAT
    GCGATAGCGGTCGCTTCTGCTAAAAATCAAACAGTTGAGTTTGATAAAGTTAACATAGGT
    GGAGAAAGTTTTAAATACAGAAATATAGGGGCCTTTTTCGATAAGAATAAAATCACAACA
    AATGAAGATGGAACAAAAGCTCCTAGTAAATTAAAATTTGTATATATAGGCAAGGGGCAA
    GACCAAGATTTGATAGGTTTGGATCTTAGGGGCAAAATTGCAGTAATGGATAGAATTTAT
    ACAAAGGATTTAAAAAATGCTTTTAAAAAAGCTATGGATAAGGGTGCACGCGCCATTATG
    GTTGTAAATACTGTAAATTACTACAATAGAGATAATTGGACAGAGCTTCCAGCTATGGGA
    TATGAAGCGGATGAAGGTACTAAAAGTCAAGTGTTTTCAATTTCAGGAGATGATGGTGTA
    AAGCTATGGAACATGATTAATCCTGATAAAAAAACTGAAGTCAAAAGAAATAATAAAGAA
    GATTTTAAAGATAAATTGGAGCAATACTATCCAATTGATATGGAAAGTTTTAATTCCAAC
    AAACCGAATGTAGGTGACGAAAAAGAGATTGACTTTAAGTTTGCACCTGACACAGACAAA
    GAACTCTATAAAGAAGATATCATCGTTCCAGCAGGATCCACATCTTGGGGGCCAAGAATA
    GATTTACTTTTAAAACCCGATGTTTCAGCACCTGGTAAAAATATTAAATCTACGCTTAAT
    GTTATTAATGGCAAATCAACTTATGGCTATATGTCAGGAACTAGTATGGCGACTCCAATC
    GTGGCAGCTTCTACTGTTTTGATTAGACCGAAATTAAAGGAAATGCTTGAAAGACCTGTA
    TTGAAAAATCTTAAGGGAGATGACAAAATAGATCTTACAAGTCTTACAAAAATTGCCCTA
    CAAAATACTGCTCGACCTATGATGGATGCAACTTCTTGGAAAGAAAAAAGTCAATACTTT
    GCATCACCTAGACAACAGGGAGCAGGCCTAATTAATGTGGCCAATGCTTTGAGAAATGAA
    GTTGTAGCAACTTTCAAAAACACTGATTCTAAAGGTTTGGTAAACTCATATGGTTCCATT
    TCTCTTAAAGAAATAAAAGGTGATAAAAAATACTTTACAATCAAGCTTCACAATACATCA
    AACAGACCTTTGACTTTTAAAGTTTCAGCATCAGCGATAACTACAGATTCTCTAACTGAC
    AGATTAAAACTTGATGAAACATATAAAGATGAAAAATCTCCAGATGGTAAGCAAATTGTT
    CCAGAAATTCACCCAGAAAAAGTCAAAGGAGCAAATATCACATTTGAGCATGGTACTTTC
    ACTATAGGCGCAAATTCTAGCTTTGATTTGAATGCGGTTATAAATGTTGGAGAGGCCAAA
    AACAAAAATAAATTTGTAGAATCATTTATTCATTTTGAGTCAGTGGAAGAAATGGAAGCT
    CTAAACTCCAACGGGAAGAAAATAAACTTCCAACCTTCTTTGTCGATGCCTCTAATGGGA
    TTTGCTGGGAATTGGAACCACGAACCAATCCTTGATAAATGGGCTTGGGAAGAAGGGTCA
    AGATCAAAAACACTGGGAGGTTATGATGATGATGGTAAACCGAAAATTCCAGGAACCTTA
    AATAAGGGAATTGGTGGAGAACATGGTATAGATAAATTTAATCCAGCAGGAGTTATACAA
    AATAGAAAAGATAAAAATACAACATCCCTGGATCAAAATCCAGAATTATTTGCTTTCAAT
    AACCAAGGGATCAACGCTCCATCATCAAGTGGTTCTAAGATTGCTAACATTTATCCTTTA
    GATTCAAATGGAAATCCTCAAGATGCTCAACTTGAAAGAGGATTAACACCTTCTCCACTT
    GTATTAAGAAGTGCAGAAGAAGGATTGATTTCAATAGTAAATACAAATAAAGAGGGAGAA
    AATCAAAGAGACTTAAAAGTCATTTCGAGAGAACACTTTATTAGAGGAATTTTAAATTCT
    AAAAGCAATGATGCAAAGGGAATCAAATCATCTAAACTAAAAGTTTGGGGTGACTTGAAG
    TGGGATGGACTCATCTATAATCCTAGAGGTAGAGAAGAAAATGCACCAGAAAGTAAGGAT
    AATCAAGATCCTGCTACTAAGATAAGAGGTCAATTTGAACCGATTGCGGAAGGTCAATAT
    TTCTATAAATTTAAATATAGATTAACTAAAGATTACCCATGGCAGGTTTCCTATATTCCT
    GTAAAAATTGATAACACCGCCCCTAAGATTGTTTCGGTTGATTTTTCAAATCCTGAAAAA
    ATTAAGTTGATTACAAAGGATACTTATCATAAGGTAAAAGATCAGTATAAGAATGAAACG
    CTATTTGCGAGAGATCAAAAAGAACATCCTGAAAAATTTGACGAGATTGCGAACGAAGTT
    TGGTATGCTGGCGCCGCTCTTGTTAATGAAGATGGAGAGGTTGAAAAAAATCTTGAAGTA
    ACTTACGCAGGTGAGGGTCAAGGAAGAAATAGAAAACTTGACAAAGACGGAAATACCATT
    TATGAAATTAAAGGTGCAGGAGATTTAAGAGGAAAAATCATTGAAGTCATTGCATTAGAT
    GGTTCTAGCAATTTCACAAAGATTCATAGAATTAAATTTGCTGATCAGGCTGATGAAAAG
    GGGATGATTTCTTATTACCTAGTAGATCCTGACAAAGATGCTTCTAAATATGAAAAACTT
    GGTGAAATTTCTGAAGATAAACTCAAAAATGCAAAGAGCCCAGAGGAAAATACCAATAAT
    AATCAAGCTAAGGATGAAGATTCAAAACCAGATGAAAAAAGTTCAGTTGAGGGAGAAGCT
    AGCCTTGAAATAAATAAAACTATTTCAACAATTAGAGAGTTTGAAAATAAAGACCTAAAG
    AAACTCATTAAAAAGAAATTTAGAGAAGTTAATGATTTTACAAGTGAAACTGGTAAGAGA
    ATAGAGGAATACGATTATAAATACGATGATAAGGGAAATATTATTGCTTATGACGATGGT
    AGTGCCTTACAATATGAAACTGAAAAATTTGACGAAATAAAATCAAAAATTTATGGTGTT
    CTAAGCCCATCTAAAGATGGACACTTTGAAATTCTTGGAAAGATAAGCAATGTTTCTAAA
    AATGCCAAGGTATATTATGGAAATAGCTATAAATCGATAGAAATCAAAGCGACTAAGTAT
    GATTCACATTCAAAAACGATGATATTTGATTTATACGCTAATATTAATGATATTGTAGAT
    GGATTAGCTTTTGCTGGAGATATGAGATTATTTGTTAAAGATGACAATCAAATAAAAGCT
    GAAACTAAGATTAGAATGCCTGAAAAAAATAAGGAAACTAAAGCAGAATATCCCTATGTA
    TCAAGTTATGGGAATGTAATCGAATTAGGAGAAGGAGATCTTTCAAAGAACAAACCAGAC
    AATTTAACTAAAATGGAATCTGGTAAAATCTATTCTGATTCAGAAAAACAACAATATCTG
    TTAAAGGATAACATCATTCTAAGAAAAGGCTATGCACTAAAAGTGACTACCTATAATCCT
    GGAAAAACGGATATGTTAGAAGGAAATGGAGTCTATAGCAAGGAAGATATAGCAAAAATA
    CAAAAGGCCAATCCTAATCTAAGAGTCCTTTCAGAAACAACAATTTATGCTGATAGTAGA
    AATGTTGAAGATGGAAGAAGTACCCAAGCTGTATTAATGTCGGCTTTGGACGGCTTTAAC
    ATTATAAGGTATCAAGTGTTTACATTTAAAATGAACGATAAAGGGGAAGCTATCGATAAA
    GACGGAAATCTTGTGACAGATTCTTCTAAACTTGTATTATTTGGTAAGGATGATAAAGAA
    TACACTGGAGAGGATAAGTCCAATGTAGAAGCTATAAAAGAAGATGGCTCCATGTTATTT
    ATTGATACCAAACCAGTAAACCTTTCAATGGATAAGAACTACTTTAATCCATCTAAATCT
    AATAAAATTTATGTACGAAATCCAGAATTTTATTTAAGAGGTAAGATTTCTGATAAGGGT
    GGTTTTAACTGGGAATTGAGAGTTAATGAATCGGTTGTAGATAATTATTTAATCTACGGA
    GATTTACACATTGATAACACTAGAGATTTTAATATTAAGCTGAATGTTAAAGACGGTGAC
    ATCATGGACTGGGGAATGAAAGACTATAAAGCAAACGGATTTCCAGATAAGGTAACAGAT
    ATGGATGGAAATGTTTATCTTCAAACTGGCTATAGCGATTTGAATGCTAAAGCAGTTGGA
    GTCCACTATCAGTTTTTATATGATAATGTTAAACCTGAAGTAAACATTGATCCTAAGGGA
    AATACTAGTATCGAATATGCTGATGGAAAATCTGTAGTCTTTAACATCAATGATAAAAGA
    AATAATGGATTCGATGGTGAGATTCAAGAACAACATATTTATGTAAATGGAAAAGAATAT
    ACATCATTTGATGATATTAAACAAATAACAGACAAGACACTAAACATTAAGATTGTTGTA
    AAAGATTTTGCAAGAAATACAACCGTAAAAGAATTCATTTTAAATAAAGATACGGGAGAG
    GTAAGTGAATTAAAACCTCATAGGGTAACTGTGACCATTCAAAATGGAAAAGAAATGAGT
    TCAACGATAGTGTCGGAAGAAGATTTTATTTTACCTGTTTATAAGGGTGAATTAGAAAAA
    GGATACCAATTTGATGGTTGGGAAATTTCTGGTTTCGAAGGTAAAAAAGACGCTGGCTAT
    GTTATTAATCTATCAAAAGATACCTTTATAAAACCTGTATTCAAGAAAATAGAGGAGAAA
    AAGGAGGAAGAGAATAAACCTACTTTTGATGTATCGAAAAAGAAAGATAACCCACAAGTA
    AATCATAGTCAATTAAATGAAAGTCACAGAAAAGAGGATTTACAAAGAGAAGATCATTCA
    CAAAAATCTGATTCAACTAAGGATGTTACAGCTACAGTTCTTGATAAAAACAATATCAGT
    AGTAAATCAACTACTAACAATCCTAATAAGTTGCCAAAAACTGGAACAGCAAGCGGAGCC
    CAGACACTATTAGCTGCCGGAATAATGTTTATAGTAGGAATTTTTCTTGGATTGAAGAAA
    AAAAATCAAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
    4560
    4620
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    4740
    4800
    4860
    4920
    4980
    5040
    5100
    5160
    5220
    5280
    5340
    5400
    5460
    5520
    5580
    5640
    5700
    5760
    5820
    5880
    5940
    6000
    6060
    6120
    6180
    6240
    6300
    6360
    6420
    6435

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPV_RS03005 [old locus tag: SPV_0558 ]
  • symbol: SPV_RS03005
  • description: S8 family serine peptidase
  • length: 2144
  • theoretical pI: 5.9964
  • theoretical MW: 240436
  • GRAVY: -0.740159

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 63.6)
    Genetic information processing Protein fate Protein modification and repair type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 63.6)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 24)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Peptidase_S8; Subtilase family (PF00082; HMM-score: 123.9)
    E-set (CL0159) fn3_5; Fn3-like domain (PF06280; HMM-score: 109.6)
    and 4 more
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 27.2)
    Leu-IlvD (CL0364) PA; PA domain (PF02225; HMM-score: 23.8)
    PPP-I (CL0570) Inhibitor_I9; Peptidase inhibitor I9 (PF05922; HMM-score: 19.6)
    no clan defined DUF6061; Family of unknown function (DUF6061) (PF19537; HMM-score: 12.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helix: 1
  • SignalP: Signal peptide SP(Sec/SPI) length 27 aa
    • SP(Sec/SPI): 0.962371
    • TAT(Tat/SPI): 0.003345
    • LIPO(Sec/SPII): 0.026751
    • Cleavage Site: CS pos: 27-28. VLA-DT. Pr: 0.8964
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000750085 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKVVVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKGLSNLKNTKVLYTYDRIFNGSAIETTPDNLDKIKQIEGISSIERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPEIHPEKVKGANITFEHGTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFADQADEKGMISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGEASLEINKTISTIREFENKDLKKLIKKKFREVNDFTSETGKRIEEYDYKYDDKGNIIAYDDGSALQYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEIKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKETKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGLKKKNQD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

G Bethe, R Nau, A Wellmer, R Hakenbeck, R R Reinert, H P Heinz, G Zysk
The cell wall-associated serine protease PrtA: a highly conserved virulence factor of Streptococcus pneumoniae.
FEMS Microbiol Lett: 2001, 205(1);99-104
[PubMed:11728722] [WorldCat.org] [DOI] (P p)Shaper Mirza, Landon Wilson, William H Benjamin, Jan Novak, Stephen Barnes, Susan K Hollingshead, David E Briles
Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.
Infect Immun: 2011, 79(6);2440-50
[PubMed:21422179] [WorldCat.org] [DOI] (I p)Sacha F de Stoppelaar, Hester J Bootsma, Aldert Zomer, Joris J T H Roelofs, Peter W M Hermans, Cornelis van 't Veer, Tom van der Poll
Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.
PLoS One: 2013, 8(11);e80062
[PubMed:24244609] [WorldCat.org] [DOI] (I e)

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