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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-JAN-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae A026
  • locus tag: T308_RS03060 [old locus tag: T308_03025 ]
  • pan locus tag?: PNEUPAN001574000
  • symbol: T308_RS03060
  • pan gene symbol?: prtA
  • synonym:
  • product: S8 family serine peptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: T308_RS03060 [old locus tag: T308_03025 ]
  • symbol: T308_RS03060
  • product: S8 family serine peptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 583970..590401
  • length: 6432
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_022655 (583970..590401) NCBI
  • BioCyc: T308_RS03060 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0558 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
    5761
    5821
    5881
    5941
    6001
    6061
    6121
    6181
    6241
    6301
    6361
    6421
    ATGAAAAAAAGTACAGTATTGTCATTAACCACAGCTGCAGTTATTTTAGCAGCCTATGCC
    CCTAATGAGGTAGTCTTAGCAGACACATCTAACTCTGAAGATGCTTTAAACATCTCTGAT
    AAAGAAAAAGTAGTATTAGATAAGGAAACAGAAAATAAAGAGAAACATGAAGATATTCAT
    AATGCTATAGAAACTTCACAGGATTTTAAAGAGAAGAAAACAGCAGTCATTGAGGGAAAA
    GCAGTTGTTAGTAAAAATCCTGTGACAGACAATAACACTAGCAATGAAGAAGCAAGAATC
    AAAGAAGATTCCAATCAATCCCAAGGAGATCATACGGACTCATTTGTGAATAAAAACACA
    GAAAATCCCAAAAAAGAAGATAAAGTTGTCTATATTGCTGAATTTAAAGATAAAGAATCT
    GGAGAAAAAGCAATCAAGCAACTATCCAATCTTAAGAATACAAAAGTTTTATATACTTAT
    GATAGAATTTTTAACGGTAGTGCCATAGAAACAACTCCAGATAACTTGGACAAAATTAAA
    CAAATAGAAGGTATTACATCGGTTGAAAGGGCACAAAAAGTCCAACCCATGATGAATCAT
    GCCAGAAAGGAAATTGGAGTTGAGGAAGCTATTGATTACCTAAAGTCTATCAATGCTCCG
    TTTGGGAAAAATTTTGATGGTAGAGGTATGGTCATTTCAAATATCGATACTGGAACAGAT
    TATAGACATAAGGCTATGAGAATCGATGATGATGCCAAAGCCTCAATGAGATTTAAAAAA
    GAAGACTTAAAAGGAACTGATAAAAATTATTGGTTGAGTGATAAAATCCCTCATGCGTTC
    AATTATTATAATGGTGGCAAAATCACTGTAGAAAAATATGATGATGGAAGGGATTATTTT
    GACCCACATGGGATGCATATTGCAGGGATTCTTGCTGGAAATGATACTGAACAAGATATC
    AAAAACTTTAACGGCATAGATGGAATTGCACCTAATGCACAAATTTTCTCTTACAAAATG
    TATTCTGACGCAGGATCTGGGTTTGCGGGTGATGAAACAATGTTTCATGCTATTGAAGAT
    TCTATCAAACACAACGTTGATGTTGTTTCGGTATCATCTGGTTTTACAGGAACAGGTCTT
    GTAGGTGAGAAATATTGGCAAGCTATTAGGGCATTAAGAAAAGCAGGCATTCCAATGGTT
    GTCGCTACGGGTAACTATGCGACTTCTGCTTCAAGTTCTTCATGGGATTTAGTAGCAAAT
    AATCATCTGAAAATGACCGACACTGGAAATGTAACACGAACTGCAGCACATGAGGATGCG
    ATAGCGGTCGCTTCTGCTAAAAATCAAACAGTTGAGTTTGATAAAGTTAACATAGGTGGA
    GAAAGTTTTAAATACAGAAATATAGGGGCCTTTTTCGATAAGAATAAAATCACAACAAAT
    GAAGATGGAACAAAAGCTCCTAGTAAATTAAAATTTGTATATATAGGCAAGGGGCAAGAC
    CAAGATTTGATAGGTTTGGATCTTAGGGGCAAAATTGCAGTAATGGATAGAATTTATACA
    AAGGATTTAAAAAATGCTTTTAAAAAAGCTATGGATAAGGGTGCACGCGCCATTATGGTT
    GTAAATACTGTAAATTACTACAATAGAGATAATTGGACAGAGCTTCCAGCTATGGGATAT
    GAAGCGGATGAAGGTACTAAAAGTCAAGTGTTTTCAATTTCAGGAGATGATGGTGTAAAG
    CTATGGAACATGATTAATCCTGATAAAAAAACTGAAGTCAAAAGAAATAATAAAGAAGAT
    TTTAAAGATAAATTGGAGCAATACTATCCAATTGATATGGAAAGTTTTAATTCCAACAAA
    CCGAATGTAGGTGACGAAAAAGAGATTGACTTTAAGTTTGCACCTGACACAGACAAAGAA
    CTCTATAAAGAAGATATCATCGTTCCAGCAGGATCCACATCTTGGGGGCCAAGAATAGAT
    TTACTTTTAAAACCCGATGTTTCAGCACCTGGTAAAAATATTAAATCTACGCTTAATGTT
    ATTAATGGCAAATCAACTTATGGCTATATGTCAGGAACTAGTATGGCGACTCCAATCGTG
    GCAGCTTCTACTGTTTTGATTAGACCGAAATTAAAGGAAATGCTTGAAAGACCTGTATTG
    AAAAATCTTAAGGGAGATGACAAAATAGATCTTACAAGTCTTACAAAAATTGCCCTACAA
    AATACTGCTCGACCTATGATGGATGCAACTTCTTGGAAAGAAAAAAGTCAATACTTTGCA
    TCACCTAGACAACAGGGAGCAGGCCTAATTAATGTGGCCAATGCTTTGAGAAATGAAGTT
    GTAGCAACTTTCAAAAACACTGATTCTAAAGGTTTGGTAAATTCATATGGTTCCATTTCT
    CTTAAAGAAATAAAAGGTGATAAAAAATACTTTACAATTAAGCTTCACAATACATCCAAC
    AGGCCTTTAACCTTTAAAGTTTCAGCATCAGCGGTAACTACAGATTCTCTAACTGACAGA
    CTAAAACTGGATGAAACATATAAAGATGAAAAATCTCCAGATGGTAAGCAAATTGTTCCA
    GAAATTCATCCAGAAAAAGTCAAAGGGGCAAATATTACATTTGAGCATGACACTTTCACT
    ATAGGGGCAAATTCTAGCTTTGATTTAAATGCGGTTATAAATGTTGGGGAGGCTAAAAAT
    AAAAATAAATTTGTAGAATCATTTATTCATTTTGAGTCAGTAGAAGAAATGGAAGCATTA
    AGCTCCAATGGCAAGAAAACCGACTTCCAACCATCTTTATCAATGCCCCTAATGGGATTT
    GCTGGGAATTGGAACCACGAACCAATCCTTGATAAATGGGCTTGGGAAGAAGGATCAAAA
    TCAAAAACAATGGAAGGTTATGATGATGACGGTAAACCAAAAATTCCAGGAACCTTAAAT
    AAGGGGATTGGTGGAGAACATGGTATAGATAAATTTAATCCAGCAGGAGTTATCCAAAAT
    AGAAAAGATAAAAATAGAACATCTCTAGATCAAGATCCAGACTTATTTGCCTTTAACAAC
    CAAGGTGTTCATGCAGAATCCACTAGTGGTTCTAAGATTGCTAACATTTATCCTTTAGAT
    TCAAATGGAAATCCTCAAGATGCTCAACTAGAAAGAGGACTAACTCCATCTCCACTTGTT
    CTAAGAAGTGCAGAAGAAGGACTAATTTCAATTGTAAACACCAACAAAGAAGGAGAAAAC
    CAAAAAGACCTTAAAGTTGTATCAAGAGAGCACTTCATAAGAGGAATTCTAAATTCTAAG
    GGAAATGACGCTAAGGGTATCAAATCATCCAAACTAAAAGTTTGGGGTGACTTGAAATGG
    GATGGACTCATCTATAACCCAAGAGGTAGAGAAGAAAATGCCCCAGAAAGTAAGGATAAC
    CAAGATCCAGCTACTAAGATACGAGGACAATTTGAACCGATTGCGGAAGGTCAATATTTC
    TATAAATTTAAATATAGATTAACTAAAGATTACCCATGGCAGGTTTCCTATATTCCTGTA
    AAAATTGATAACACAGCCCCTAAGATTGTTTCGGTTGATTTTTCAAATCCTGAAAAAATT
    AAGCTAATCACAAAGGATACTTATCACAAGGTAAAAGATCAATACAAGAATGAAACTTTA
    TTTGCTAGAGATCAAAAAGAACATCCTGAAAAATTTGATGAGATTGCAAATGAGGTGTGG
    TATGCAGGAGCTGCTCTTGTTAATGAAGATGGAGAGGTTGAGAAAAATCTTGAAGTAACT
    TATGCAGGTGAGGGTCAAGGAAGAAATAGGAAGCTTGATAAAGATGGGAATACTATCTAT
    GAAATTAGCGGAGCAGGAGATCTAAGAGGAAAAATCATCGAAGTAATCGCCCTAGATGGA
    GCAAGCAACTTTACCAAAATCCATAGGATTAAATTTGCTAATCAAGCTGATGAAAAAGGG
    ATGATTTCCTATTATCTAGTAGATCCTGATCAGGATTCATCTAAATACCAAAAGCTTGGC
    GAAATTCCTGAATCTAAATTTAAGAATTTAAAAAATGTTAAAGATGATAGCCTAAACAAA
    GAGACAGCTGAGGTGGAAAATAACCTTTTAGTAGATAATCAGTCTATCGAAGGAAAATCT
    CTCTTTAATATTCATAAAACTATTTCAACAATTAGAGACTTTGAAAATAAAGACCTAAAG
    AAACTCATTAAAAAGAAATATAAGCAAGAAGACGACTTTGTAAATGGTGGAACAAGAACA
    GTAGAGCGTGATTATAAATACGATGATAAAGGAAATATAATAGCCTACGATGATGGGACT
    GATCTAGAATATGAAACTGAGAAACTTGACGAAATCAAATCAAAAATTTATGGTGTTCTA
    AGTCCGTCTAAAGATGGACACTTTGAAATTCTTGGAAAGATAAGTAATGTTTCTAAAAAT
    GCCAAGGTATATTATGGGAATAACTATAAATCTATAGAAATCAAAGCGACCAAGTATGAT
    TTCCACTCAAAAACGATGACATTTGATCTATACGCTAATATTAATGATATTGTGGATGGA
    TTAGCTTTTGCAGGAGATATGAGATTATTTGTTAAAGATAATGATCAGAAAAAAGCTGAA
    ATTAAAATTAGAATGCCTGAAAAAATTAAGGAAACTAAATCAGAATATCCCTATGTATCA
    AGTTATGGGAATGTCATAGAATTAGGGGAAGGAGATCTTTCAAAAAACAAACCAGACAAT
    TTAACTAAAATGGAATCTGGAAAAATCTATTCTGATTCAGAAAAACAACAATATCTGTTA
    AAGGATAATATCATTCTAAGAAAAGGCTATGCACTAAAAGTGACTACCTATAATCCTGGA
    AAAACGGATATGTTAGAAGGAAATGGAGTCTATAGCAAGGAAGATATAGCAAAAATACAA
    AAGGCCAATCCTAATCTAAGAGTCCTTTCAGAAACAACAATTTATGCTGATAGTAGAAAT
    GTTGAAGATGGAAGAAGTACCCAAGCTGTATTAATGTCGGCTTTGGACGGCTTTAACATT
    ATAAGGTATCAAGTGTTTACATTTAAAATGAACGATAAAGGGGAAGCTATCGATAAAGAC
    GGAAATCTTGTGACAGATTCTTCTAAACTTGTATTATTTGGTAAGGATGATAAAGAATAC
    ACTGGAGAGGATAAGTCCAATGTAGAAGCTATAAAAGAAGATGGCTCCATGTTATTTATT
    GATACCAAACCAGTAAACCTTTCAATGGATAAGAACTACTTTAATCCATCTAAATCTAAT
    AAAATTTATGTACGAAATCCAGAATTTTATTTAAGAGGTAAGATTTCTGATAAGGGTGGT
    TTTAACTGGGAATTGAGAGTTAATGAATCGGTTGTAGATAATTATTTAATCTACGGAGAT
    TTACACATTGATAACACTAGAGATTTTAATATTAAGCTGAATGTTAAAGACGGTGACATC
    ATGGACTGGGGAATGAAAGACTATAAAGCAAACGGATTTCCAGATAAGGTAACAGATATG
    GATGGAAATGTTTATCTTCAAACTGGCTATAGCGATTTGAATGCTAAAGCAGTTGGAGTC
    CACTATCAGTTTTTATATGATAATGTTAAACCCGAAGTAAACATTGATCCTAAGGGAAAT
    ACTAGTATCGAATATGCTGATGGAAAATCTGTAGTCTTTAACATCAATGATAAAAGAAAT
    AATGGATTCGATGGTGAGATTCAAGAACAACATATTTATGTAAATGGAAAAGAATATACA
    TCATTTGATGATATTAAACAAATAACAGACAAGACACTAAACATTAAGATTGTTGTAAAA
    GATTTTGCAAGAAATACAACCGTAAAAGAATTCATTTTAAATAAAGATACGGGAGAGGTA
    AGTGAATTAAAACCTCATAGGGTAACTGTGACCATTCAAAATGGAAAAGAAATGAGTTCA
    ACGATAGTGTCGGAAGAAGATTTTATTTTACCTGTTTATAAGGGTGAATTAGAAAAAGGA
    TACCAATTTGATGGTTGGGAAATTTCTGGTTTCGAAGGTAAAAAAGACGCTGGCTATGTT
    ATTAATCTATCAAAAGATACCTTTATAAAACCTGTATTCAAGAAAATAGAGGAGAAAAAG
    GAGGAAGAAAATAAACCTACTTTTGATGTATCGAAAAAGAAAGATAACCCACAAGTAAAC
    CATAGTCAATTAAATGAAAGTCACAGAAAAGAGGATTTACAAAGAGAAGATCATTCACAA
    AAATCTGATTCAACTAAGGATGTTACAGCTACAGTTCTTGATAAAAACAATATCAGTAGT
    AAATCAACTACTAACAATCCTAATAAGTTGCCAAAAACTGGAACAGCAAGCGGAGCCCAG
    ACACTATTAGCTGCCGGAATAATGTTTATAGTAGGAATTTTTCTTGGATTGAAGAAAAAA
    AATCAAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
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    1320
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    1560
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    1980
    2040
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    2160
    2220
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    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
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    3840
    3900
    3960
    4020
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    4140
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    4260
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    5220
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    5460
    5520
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    5700
    5760
    5820
    5880
    5940
    6000
    6060
    6120
    6180
    6240
    6300
    6360
    6420
    6432

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: T308_RS03060 [old locus tag: T308_03025 ]
  • symbol: T308_RS03060
  • description: S8 family serine peptidase
  • length: 2143
  • theoretical pI: 6.06479
  • theoretical MW: 240586
  • GRAVY: -0.732664

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 63.7)
    Genetic information processing Protein fate Protein modification and repair type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 63.7)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 24)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Peptidase_S8; Subtilase family (PF00082; HMM-score: 123.8)
    E-set (CL0159) fn3_5; Fn3-like domain (PF06280; HMM-score: 110.1)
    and 3 more
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 27.2)
    Leu-IlvD (CL0364) PA; PA domain (PF02225; HMM-score: 24)
    PPP-I (CL0570) Inhibitor_I9; Peptidase inhibitor I9 (PF05922; HMM-score: 19.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helix: 1
  • SignalP: Signal peptide SP(Sec/SPI) length 27 aa
    • SP(Sec/SPI): 0.96653
    • TAT(Tat/SPI): 0.002764
    • LIPO(Sec/SPII): 0.022977
    • Cleavage Site: CS pos: 27-28. VLA-DT. Pr: 0.9105
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000750030 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKSTVLSLTTAAVILAAYAPNEVVLADTSNSEDALNISDKEKVVLDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKAVVSKNPVTDNNTSNEEARIKEDSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTYDRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGKQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGKPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAESTSGSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHFIRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQGRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISYYLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLFNIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGTDLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKATKYDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKSEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGLKKKNQD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

G Bethe, R Nau, A Wellmer, R Hakenbeck, R R Reinert, H P Heinz, G Zysk
The cell wall-associated serine protease PrtA: a highly conserved virulence factor of Streptococcus pneumoniae.
FEMS Microbiol Lett: 2001, 205(1);99-104
[PubMed:11728722] [WorldCat.org] [DOI] (P p)Shaper Mirza, Landon Wilson, William H Benjamin, Jan Novak, Stephen Barnes, Susan K Hollingshead, David E Briles
Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.
Infect Immun: 2011, 79(6);2440-50
[PubMed:21422179] [WorldCat.org] [DOI] (I p)Sacha F de Stoppelaar, Hester J Bootsma, Aldert Zomer, Joris J T H Roelofs, Peter W M Hermans, Cornelis van 't Veer, Tom van der Poll
Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.
PLoS One: 2013, 8(11);e80062
[PubMed:24244609] [WorldCat.org] [DOI] (I e)

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