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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NU83127
  • locus tag: EL277_RS03225 [old locus tag: SPNU_0605 ]
  • pan locus tag?: PNEUPAN001574000
  • symbol: EL277_RS03225
  • pan gene symbol?: prtA
  • synonym:
  • product: S8 family serine peptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL277_RS03225 [old locus tag: SPNU_0605 ]
  • symbol: EL277_RS03225
  • product: S8 family serine peptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 609452..615871
  • length: 6420
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018936 (609452..615871) NCBI
  • BioCyc: EL277_RS03225 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0558 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
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    3541
    3601
    3661
    3721
    3781
    3841
    3901
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    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
    5761
    5821
    5881
    5941
    6001
    6061
    6121
    6181
    6241
    6301
    6361
    ATGAAAAAAAGTACAGTATTGTCATTAACCACAGCTGCAGTTATTTTAGCAGCCTATGCC
    CCTAATGAGGTAGTCTTAGCAGACACATCTAGCTCTGAAGATGCTTTAAGCATCTCTGAT
    AAAGAAAAAGTAGCAGAAAATAAAGAGAAACATGAAGATATCCATAGTGCTATGGAAACT
    TCAAAGGATACTGAAGAAAAGAAAGCAACAGTTATTGAGGAAAAAGAAGTTGTTAGTAAA
    AATCCTGTGATAGACACTAAAACTAGCAATGAAGAAGCAAGAATCAAAGAAGATTCCAAT
    CAATCCCAAGGAGATAATGCACACTCGTCTGCAAATAAAGGCACAGAAAATCCCAAAAAA
    GAAGATAGACTTGTCTATATTGCTGAATTTAAAGATAAAGAATCTGGAGAAAAAGCAATC
    AAGGAACTATCCAGTCTTAAGAATACAAAAGTTTTATATACTTATGATAGAATTTTTAAC
    GGTAGTGCCATAGAAACAACTCCAGATAACTTGGACAAAATTAAACAAATAGAAGGTATT
    TCATCGGTTGAAAGGGCACAAAAAGTCCAACCCATGATGAATCATGCCAGAAAGGAAATT
    GGAGTTGAGGAAGCTATTGATTACCTAAAGTCTATCAATGCTCCATTTGGGAAAAATTTT
    GATGGTAGAGGTATGGTCATTTCAAATATCGATACTGGAACAGATTATAGACATAAGGCT
    ATGAGAATCGATGATGATGCCAAAGCCTCAATGAGATTTAAAAAAGAAGACTTAAAAGGA
    ACTGATAAAAATTATTGGTTGAGTGATAAAATCCCTCATGCGTTCAATTATTATAATGGT
    GGCAAAATCACTGTAGAAAAATATGATGATGGAAGGGATTATTTTGACCCACATGGGATG
    CATATTGCAGGGATTCTTGCTGGAAATGATACTGAACAAGATATCAAAAACTTTAACGGC
    ATAGATGGAATTGCACCTAATGCACAAATTTTCTCTTACAAAATGTATTCTGACGCAGGA
    TCTGGGTTTGCGGGTGATGAAACAATGTTTCATGCTATTGAAGATTCTATCAAACACAAC
    GTTGATGTTGTTTCGGTATCATCTGGTTTTACAGGAACAGGTCTTGTAGGTGAGAAATAT
    TGGCAAGCTATTCGGGCATTAAGAAAAGCAGGCATTCCAATGGTTGTCGCTACGGGTAAC
    TATGCGACTTCTGCTTCAAGTTCTTCATGGGATTTAGTAGCAAATAATCATCTGAAAATG
    ACCGACACTGGAAATGTAACACGAACTGCAGCACATGAAGATGCTATAGCGGTCGCTTCT
    GCTAAAAATCAAACAGTTGAGTTTGATAAAGTTAACATAGGTGGAGAAAGTTTTAAATAC
    AGAAATATAGGGGCCTTTTTCGATAAGAATAAAATCACAACAAATGAAGATGGAACAAAA
    GCTCCTAGTAAATTAAAATTTGTATATATAGGCAAGGGGCAAGACCAAGATTTGATAGGT
    TTGGATCTTAGGGGCAAAATTGCAGTAATGGATAGAATTTATACAAAGGATTTAAAAAAT
    GCTTTTAAAAAAGCTATGGATAAGGGTGCACGCGCCATTATGGTTGTAAATACTGTAAAT
    TACTACAATAGAGATAATTGGACAGAGCTTCCAGCTATGGGATATGAAGCGGATGAAGGT
    ACTAAAAGTCAAGTGTTTTCAATTTCAGGAGATGATGGTGTAAAGCTATGGAACATGATT
    AATCCTAATAAAAAAACTGAAGTCAAAAGAAATAATAAAGAAGATTTTAAAGATAAATTG
    GAGCAATACTATCCAATTGATATGGAAAGTTTTAATTCCAACAAACCGAATGTAGGTGAC
    GAAAAAGAGATTGACTTTAAGTTTGCACCTGACACAGACAAAGAACTCTATAAAGAAGAT
    ATCATCGTTCCAGCAGGATCTACATCTTGGGGGCCAAGAATAGATTTACTTTTAAAACCC
    GATGTTTCAGCACCTGGTAAAAATATTAAATCCACGCTTAATGTTATTAATGGCAAATCA
    ACTTATGGCTATATGTCAGGAACTAGTATGGCGACTCCAATCGTGGCAGCTTCTACTGTT
    TTGATTAGACCGAAATTAAAGGAAATGCTTGAAAGACCTGTATTGAAAAATCTTAAGGGA
    GATGACAAAATAGACCTTACAAGTCTTACAAAAATTGCCCTACAAAATACTGCGCGACCT
    ATGATGGATGCAACTTCTTGGAAAGAAAAAAGTCAATACTTTGCATCACCTAGACAACAG
    GGAGCAGGCCTAATTAATGTGGCCAATGCTTTGAGAAATGAAGTTGTAGCAACTTTCAAA
    AACACTGATTCTAAAGGTTTGGTAAACTCATATGGTTCCATTTCTCTTAAAGAAATAAAA
    GGTGATAAAAAATACTTTACAATCAAGCTTCACAATACATCAAACAGACCTTTGACTTTT
    AAAGTTTCAGCATCAGCGATAACTACAGATTCTTTAACTGACAGATTAAAACTTGATGAA
    ACATATAAAGATGAAAAATCTCCAGATGGTAAGCAAATTGTTCCAGAAATTCACCCAGAA
    AAAGTCAAAGGAGCAAATATCACATTTGAGCATGATACTTTCACTATAGGCGCAAATTCT
    AGCTTTGATTTGAATGCGGTTATAAATGTTGGAGAGGCCAAAAACAAAAATAAATTTGTA
    GAATCATTTATTCATTTTGAGTCAGTGGAAGAAATGGAAGCTCTAAACTCCAACGGGAAG
    AAAATAAACTTCCAACCTTCTTTGTCGATGCCTCTAATGGGATTTGCTGGGAATTGGAAC
    CACGAACCAATCCTTGATAAATGGGCTTGGGAAGAAGGGTCAAGATCAAAAACACTGGGA
    GGTTATGATGATGATGGTAAACCGAAAATTCCAGGAACCTTAAATAAGGGAATTGGTGGA
    GAACATGGTATAGATAAATTTAATCCAGCAGGAGTTATACAAAATAGAAAAGATAAAAAT
    ACAACATCCCTGGATCAAAATCCAGAATTATTTGCTTTCAATAACCAAGGGATCAACGCT
    CCATCATCAAGTGGTTCTAAGATTGCTAACATTTATCCTTTAGATTCAAATGGAAATCCT
    CAAGATGCTCAACTTGAAAGAGGATTAACACCTTCTCCACTTGTATTAAGAAGTGCAGAA
    GAAGGATTGATTTCAATAGTAAATACAAATAAAGAGGGAGAAAATCAAAGAGACTTAAAA
    GTCATTTCGAGAGAACACTTTATTAGAGGAATTTTAAATTCTAAAAGCAATGATGCAAAG
    GGAATCAAATCATCTAAACTAAAAGTTTGGGGTGACTTGAAGTGGGATGGACTCATCTAT
    AATCCTAGAGGTAGAGAAGAAAATGCACCAGAAAGTAAGGATAATCAAGATCCTGCTACT
    AAGATAAGAGGTCAATTTGAACCGATTGCGGAAGGTCAATATTTCTATAAATTTAAATAT
    AGATTAACTAAAGATTACCCATGGCAGGTTTCCTATATTCCTGTAAAAATTGATAACACC
    GCCCCTAAGATTGTTTCGGTTGATTTTTCAAATCCTGAAAAAATTAAGTTGATTACAAAG
    GATACTTATCATAAGGTAAAAGATCAGTATAAGAATGAAACGCTATTTGCGAGAGATCAA
    AAAGAACATCCTGAAAAATTTGACGAGATTGCGAACGAAGTTTGGTATGCTGGCGCCGCT
    CTTGTTAATGAAGATGGAGAGGTTGAAAAAAATCTTGAAGTAACTTACGCAGGTGAGGGT
    CAAGGAAGAAATAGAAAACTTGATAAAGACGGAAATACCATTTATGAAATTAAAGGTGCA
    GGAGATTTAAGAGGAAAAATCATTGAAGTCATTGCATTAGATGGTTCTAGCAATTTCACA
    AAGATTCATAGAATTAAATTTGCTGATCATGCTGATGAAAAGGGGATGATTTCTTATTAC
    CTAGTAGATCCTGATCAAGATTCATCAAAATATCAAAAGCTTGGCGAGATTGCAGAATCT
    AAATTTAAAAATTTAGGAAATGGAAAAGAGGGTAGTCTAAAAAAAGATACAACTGAGGTA
    GAACATCATCATCAAGAAAATGAAGAGTCTATTAAAGAAAAATCTAGTTTTACTATTGAT
    AGAAATATTTCAACAATTAGAGACTTTGAAAATAAAGACTTAAAGAAACTCATTAAAAAG
    AAATTTAGAGAAGTTGAGGACTTTACAAGTGAAACTGGTAAGAGGAAACAAGAATACGAT
    TATAAATACGATGATAAGGGAAATATCATTGCTTATGACGATGAAAGTGCTCTAGAATAT
    GAAACTGAAAAATTTGACGAAATAAAATCAAAAATTTATGGTGTTCTAAGCCCATCTAAA
    GATGGACACTTTGAAATTCTTGGAAAGATAAGCAATGTTTCTAAAAATGCCAAGGTATAT
    TATGGAAATAACTATAAATTTATAGAAATCAAAGCGACTAAGTATGACTCACATTCAAAA
    ACGATGACATTTGATTTATACGCTAATATTAATGATATTGTGGATGGATTAGCTTTTGCT
    GGAGATATGCGGTTTTTTGTTAAAGATGATGATCGAATAAAAGCTGAAACTAAAATTAGA
    ATGCCTGAAAAAAATAAGGAAACTAAAGCAGAATATCCCTATGTATCAAGTTATGGGAAT
    GTAATCGAATTAGGAGAAGGAGATCTTTCAAAAAACAAACCAGACAATTTAACTAAAATG
    GAATCTGGTAAAATCTATTCTGATTCAGAAAAACAACAATATCTGTTAAAGGATAATATC
    ATTCTAAGAAAAGGCTATGCACTAAAAGTGACTACCTATAATCCTGGAAAAACGGATATG
    TTAGAAGGAAATGGAGTCTATAGCAAGGAAGATATAGCAAAAATACAAAAGGCCAATCCT
    AATCTAAGAGCCCTTTCAGAAACAACAATTTATGCTGATAGTAGAAATGTTGAAGATGGA
    AGAAGTACCCAATCTGTATTAATGTCGGCTTTGGACGGCTTTAACATTATAAGGTATCAA
    GTGTTTACATTTAAAATGAACGATAAAGGGGAAGCTATCGATAAAGACGGAAATCTTGTG
    ACAGATTCTTCTAAACTTGTATTATTTGGTAAGGATGATAAAGAATACACTGGAGAGGAT
    AAGTTCAATGTAGAAGCTATAAAAGAAGATGGCTCCATGTTATTTATTGATACCAAACCA
    GTAAACCTTTCAATGGATAAGAACTACTTTAATCCATCTAAATCTAATAAAATTTATGTA
    CGAAATCCAGAATTTTATTTAAGAGGTAAGATTTCTGATAAGGGTGGTTTTAACTGGGAA
    TTGAGAGTTAATGAATCGGTTGTAGATAATTATTTAATCTACGGAGATTTACACATTGAT
    AACACTAGAGATTTTAATATTAAGCTGAATGTTAAAGACGGTGACATCATGGACTGGGGA
    ATGAAAGACTATAAAGCAAACGGATTTCCAGATAAGGTAACAGATATGGATGGAAATGTT
    TATCTTCAAACTGGCTATAGCGATTTGAATGCTAAAGCAGTTGGAGTCCACTATCAGTTT
    TTATATGATAATGTTAAACCCGAAGTAAACATTGATCCTAAGGGAAATACTAGTATCGAA
    TATGCTGATGGAAAATCTGTAGTCTTTAACATCAATGATAAAAGAAATAATGGATTCGAT
    GGTGAGATTCAAGAACAACATATTTATATAAATGGAAAAGAATATACATCATTTAATGAT
    ATTAAACAAATAATAGACAAGACACTAAACATTAAGATTGTTGTAAAAGATTTTGCAAGA
    AATACAACCGTAAAAGAATTCATTTTAAATAAAGATACGGGAGAGGTAAGTGAATTAAAA
    CCTCATAGGGTAACTGTGACCATTCAAAATGGAAAAGAAATGAGTTCAACGATAGTGTCG
    GAAGAAGATTTTATTTTACCTGTTTATAAGGGTGAATTAGAAAAAGGATACCAATTTGAT
    GGTTGGGAAATTTCTGGTTTCGAAGGTAAAAAAGACGCTGGCTATGTTATTAATCTATCA
    AAAGATACCTTTATAAAACCTGTATTCAAGAAAATAGAGGAGAAAAAGGAGGAAGAAAAT
    AAACCTACTTTTGATGTATCGAAAAAGAAAGATAACCCACAAGTAAACCATAGTCAATTA
    AATGAAAGTCACAGAAAAGAGGATTTACAAAGAGAAGAGCATTCACAAAAATCTGATTCA
    ACTAAGGATGTTACAGCTACAGTTCTTGATAAAAACAATATCAGTAGTAAATCAACTACT
    AACAATCCTAATAAGTTGCCAAAAACTGGAACAGCAAGCGGAGCCCAGACACTATTAGCT
    GCCGGAATAATGTTTATAGTAGGAATTTTTCTTGGATTGAAGAAAAAAAATCAAGATTAA
    60
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    6300
    6360
    6420

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL277_RS03225 [old locus tag: SPNU_0605 ]
  • symbol: EL277_RS03225
  • description: S8 family serine peptidase
  • length: 2139
  • theoretical pI: 6.21886
  • theoretical MW: 240283
  • GRAVY: -0.742496

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 63.6)
    Genetic information processing Protein fate Protein modification and repair type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 63.6)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 23.9)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Peptidase_S8; Subtilase family (PF00082; HMM-score: 123.4)
    E-set (CL0159) fn3_5; Fn3-like domain (PF06280; HMM-score: 110.3)
    and 3 more
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 27.2)
    Leu-IlvD (CL0364) PA; PA domain (PF02225; HMM-score: 23.6)
    PPP-I (CL0570) Inhibitor_I9; Peptidase inhibitor I9 (PF05922; HMM-score: 17.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helix: 1
  • SignalP: Signal peptide SP(Sec/SPI) length 27 aa
    • SP(Sec/SPI): 0.956806
    • TAT(Tat/SPI): 0.003913
    • LIPO(Sec/SPII): 0.030767
    • Cleavage Site: CS pos: 27-28. VLA-DT. Pr: 0.8867
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000750071 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKVAENKEKHEDIHSAMETSKDTEEKKATVIEEKEVVSKNPVIDTKTSNEEARIKEDSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKELSSLKNTKVLYTYDRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFADHADEKGMISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTEVEHHHQENEESIKEKSSFTIDRNISTIRDFENKDLKKLIKKKFREVEDFTSETGKRKQEYDYKYDDKGNIIAYDDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKETKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRALSETTIYADSRNVEDGRSTQSVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKFNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDGEIQEQHIYINGKEYTSFNDIKQIIDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREEHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGLKKKNQD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

G Bethe, R Nau, A Wellmer, R Hakenbeck, R R Reinert, H P Heinz, G Zysk
The cell wall-associated serine protease PrtA: a highly conserved virulence factor of Streptococcus pneumoniae.
FEMS Microbiol Lett: 2001, 205(1);99-104
[PubMed:11728722] [WorldCat.org] [DOI] (P p)Shaper Mirza, Landon Wilson, William H Benjamin, Jan Novak, Stephen Barnes, Susan K Hollingshead, David E Briles
Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.
Infect Immun: 2011, 79(6);2440-50
[PubMed:21422179] [WorldCat.org] [DOI] (I p)Sacha F de Stoppelaar, Hester J Bootsma, Aldert Zomer, Joris J T H Roelofs, Peter W M Hermans, Cornelis van 't Veer, Tom van der Poll
Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.
PLoS One: 2013, 8(11);e80062
[PubMed:24244609] [WorldCat.org] [DOI] (I e)

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