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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN994038
  • locus tag: SPN994038_RS03090 [old locus tag: SPN994038_05790 ]
  • pan locus tag?: PNEUPAN001574000
  • symbol: SPN994038_RS03090
  • pan gene symbol?: prtA
  • synonym:
  • product: S8 family serine peptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN994038_RS03090 [old locus tag: SPN994038_05790 ]
  • symbol: SPN994038_RS03090
  • product: S8 family serine peptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 572682..579101
  • length: 6420
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_021026 (572682..579101) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0558 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
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    2221
    2281
    2341
    2401
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    2521
    2581
    2641
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    2761
    2821
    2881
    2941
    3001
    3061
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    3181
    3241
    3301
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    3541
    3601
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    3841
    3901
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    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
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    5821
    5881
    5941
    6001
    6061
    6121
    6181
    6241
    6301
    6361
    ATGAAAAAAAGTACAGTATTGTCATTAACCACAGCTGCAGTTATTTTAGCAGCCTATGCC
    CCTAATGAGGTAGTCTTAGCAGACACATCTAACTCTGAAGATGCTTTAAGCATCTCTGAT
    AAAGAAAAAGTAGCAGAAAATAAAGAGAAACATGAAAATATCCATAGTGCTATGGAAACT
    TCACAGGATTTTAAAGAGAAGAAAACAGCAGTCATTAAGGAAAAAGAAGTTGTTAGTAAA
    AATCCTGTGATAGACAATAACACTAGCAATGAAGAAGCAAAAATCAAAGAAGAAAATTCC
    AATCAATCCCAAGGAGATTATACGGACTCATTTGTGAATAAAAACACAGAAAATCCCAAA
    AAACAAGATAAAGTTGTCTATATTGCTGAATTTAAAGATAAAGAATCTGGAGAAAAAGCA
    ATCAAGCAACTATCCAGTCTTAAGAATACAAAAGTTTTATATACTTATGATAGAATTTTT
    AACGGTAGTGCCATAGAAACAACTCCAGATAACTTGGACAAAATTAAACAAATAGAAGGT
    ATTTCATCGGTTGAAAGGGCACAAAAAGTCCAACCCATGATGAATCATGCCAGAAAGGAA
    ATTGGAGTTGAGGAAGCTATTGATTACCTAAAGTCTATCAATGCTCCGTTTGGGAAAAAT
    TTTGATGGTAGAGGTATGGTCATTTCAAATATCGATACTGGAACAGATTATAGACATAAG
    GCTATGAGAATCGATGATGATGCCAAAGCCTCAATGAGATTTAAAAAAGAAGACTTAAAA
    GGAACTGATAAAAATTATTGGTTGAGTGATAAAATCCCTCATGCGTTCAATTATTATAAT
    GGTGGCAAAATCACTGTAGAAAAATATGATGATGGAAGAGATTATTTTGACCCACATGGG
    ATGCATATTGCAGGGATTCTTGCTGGAAATGATACTGAACAAGATATCAAAAACTTTAAC
    GGCATAGATGGAATTGCACCTAATGCACAAATTTTCTCTTACAAAATGTATTCTGACGCA
    GGATCTGGGTTTGCGGGTGATGAAACAATGTTTCATGCTATTGAAGATTCTATCAAACAC
    AACGTTGATGTTGTTTCGGTATCATCTGGTTTTACAGGAACAGGTCTTGTAGGTGAGAAA
    TATTGGCAAGCTATTCGGGCATTAAGAAAAGCAGGCATTCCAATGGTTGTCGCTACGGGT
    AACTATGCGACTTCTGCTTCAAGTTCTTCATGGGATTTAGTAGCAAATAATCATCTGAAA
    ATGACCGACACTGGAAATGTAACACGAACTGCAGCACATGAAGATGCGATAGCGGTCGCT
    TCTGCTAAAAATCAAACAGTTGAGTTTGATAAGGTTAACATTGGAGGACAAAGTTTTAAA
    TACAGAAATATAGGGGCCTTTTTCGATAAGAATAAAATCACAACAAATGAAGATGGAACA
    AAAGCTCCTAGTAAATTAAAATTTGTATATATAGGCAAGGGGCAAGACCAAGATTTGATA
    GGTTTGGATCTTAGGGGCAAAATTGCAGTAATGGATAGAATTTATACAAAGGATTTAAAA
    AATGCTTTTAAAAAAGCTATGGATAAGGGTGCACGCGCCATTATGGTTGTAAATACTGTA
    AATTACTACAATAGAGATAATTGGACAGAGCTTCCAGCTATGGGATATGAAGCGGATGAA
    GGTACTAAAAGTCAAGTGTTTTCAATTTCAGGAGATGATGGTGTAAAGCTATGGAACATG
    ATTAATCCTGATAAAAAAACTGAAGTCAAAAGAAATAATAAAGAAGATTTTAAAGATAAA
    TTGGAGCAATACTATCCAATTGATATGGAAAGTTTTAATTCCAACAAACCGAATGTAGGT
    GACGAAAAAGAGATTGACTTTAAGTTTGCACCTGACACAGACAAAGAACTCTATAAAGAA
    GATATCATCGTTCCAGCAGGATCCACATCTTGGGGGCCAAGAATAGATTTACTTTTAAAA
    CCCGATGTTTCAGCACCTGGTAAAAATATTAAATCCACGCTTAATGTTATTAATGGCAAA
    TCAACTTATGGCTATATGTCCGGAACTAGTATGGCGACTCCAATCGTAGCAGCTTCTACT
    GTTTTGATTCGACCAAAATTGAAGGAAATGCTTGAAAAACCCGTATTAAAAAATCTTAAA
    GGTGATGATAAAATAGACCTTACAAGTCTTACAAAAATAGCCCTACAAAATACTGCAAGA
    CCTATGATGGATGCAACTTCTTGGAAAGAAAAAAGTCAATACTTTGCATCACCTAGACAG
    CAGGGGGCGGGGCTAATTAATGTGGCCAACGCTTTGAGAAATGAAGTTGTAGCGACTTTC
    AAAAACACGGATTCTAAAGGTTTGGTAAATTCATATGGTTCCATTTCTCTTAAAGAAATA
    AAAGGTGATAAAAAATACTTTACAATTAAGCTTCACAATACATCCAACAGGCCTTTAACC
    TTTAAAGTTTCAGCATCAGCGGTAACTACAGATTCTCTAACTGACAGACTAAAACTGGAT
    GAAACATATAAAGATGAAAAATCTCCAGATGGTAAGCAAATTGTTCCAGAAATTCATCCA
    GAAAAAGTCAAAGGGGCAAATATTACATTTGAGCATGACACTTTCACTATAGGGGCAAAT
    TCTAGCTTTGATTTAAATGCGGTTATAAATGTTGGGGAGGCTAAAAATAAAAATAAATTT
    GTAGAATCATTTATTCATTTTGAGTCAGTAGAAGAAATGGAAGCATTAAGCTCCAATGGC
    AAGAAAACCGACTTCCAACCATCTTTATCAATGCCCCTGATGGGATTTGCTGGGAATTGG
    AACCACGAACCAATCCTTGATAAATGGGCTTGGGAAGAAGGATCAAAATCAAAAACAATG
    GAAGGTTATGATGATGACGGTAAACCAAAAATTCCAGGAACCTTAAATAAGGGGATTGGT
    GGAGAACATGGTATAGATAAATTTAATCCAGCAGGAGTTATCCAAAATAGAAAAGATAAA
    AATAGAACATCTCTAGATCAAGATCCAGACTTATTTGCCTTTAACAACCAAGGTGTTCAT
    GCAGGATCCACTAGTGGTTCTAAGATTGCTAACATTTATCCTTTAGATTCAAATGGAAAT
    CCTCAAGATGCTCAACTAGAAAGAGGACTAACTCCATCTCCACTTGTTCTAAGAAGTGCA
    GAAGAAGGACTAATTTCAATTGTAAACACCAACAAAGAAGGAGAAAACCAAAAAGACCTT
    AAAGTTGTATCAAGAGAGCACTTCATAAGAGGAATTCTAAATTCTAAGGGAAATGACGCT
    AAGGGTATCAAATCATCCAAACTAAAAGTTTGGGGTGACTTGAAATGGGATGGACTCATC
    TATAACCCAAGAGGTAGAGAAGAAAATGCCCCAGAAAGTAAGGATAACCAAGATCCAGCT
    ACTAAGATACGAGGACAATTTGAACCGATTGCGGAAGGTCAATATTTCTATAAATTTAAA
    TATAGATTAACTAAAGATTACCCATGGCAGGTTTCCTATATTCCTGTAAAAATTGATAAC
    ACAGCCCCTAAGATTGTTTCGGTTGATTTTTCAAATCCTGAAAAAATTAAGCTAATCACA
    AAGGATACTTATCACAAGGTAAAAGATCAATACAAGAATGAAACTTTATTTGCTAGAGAT
    CAAAAAGAACATCCTGAAAAATTTGATGAGATTGCAAATGAGGTGTGGTATGCAGGAGCT
    GCTCTTGTTAATGAAGATGGAGAGGTTGAGAAAAATCTTGAAGTAACTTATGCAGGTGAG
    GGTCAAGGAAGAAATAGGAAGCTTGATAAAGATGGGAATACTATCTATGAAATTAGCGGA
    GCAGGAGATCTAAGAGGAAAAATCATCGAAGTAATCGCCCTAGATGGAGCAAGCAACTTT
    ACCAAAATCCATAGGATTAAATTTGCTAATCAAGCTGATGAAAAAGGGATGATTTCCTAT
    TATCTAGTAGATCCTGATCAGGATTCATCTAAATACCAAAAGCTTGGCGAAATTCCTGAA
    TCTAAATTTAAGAATTTAAAAAATGTTAAAGATGATAGCCTAAACAAAGAGACAGCTGAG
    GTGGAAAATAACCTTTTAGTAGATAATCAGTCTATCGAAGGAAAATCTCTCTTTAATATT
    CATAAAACTATTTCAACAATTAGAGACTTTGAAAATAAAGACCTAAAGAAACTCATTAAA
    AAGAAATATAAGCAAGAAGACGACTTTGTAAATGGTGGAACAAGAACAGTAGAGCGTGAT
    TATAAATACGATGATAAAGGAAATATAATAGCCTACGATGATGGGACTGATCTAGAATAT
    GAAACTGAGAAACTTGACGAAATCAAATCAAAAATTTATGGTGTTCTAAGTCCGTCTAAA
    GATGGACACTTTGAAATTCTTGGAAAGATAAGTAATGTTTCTAAAAATGCCAAGGTATAT
    TATGGGAATAACTATAAATCTATAGAAATCAAAGCGACCAAGTATGATTTCCACTCAAAA
    ACGATGACATTTGATCTATACGCTAATATTAATGATATTGTGGATGGATTAGCTTTTGCA
    GGAGATATGAGATTATTTGTTAAAGATAATGATCAGAAAAAAGCTGAAATTAAAATTAGA
    ATGCCTGAAAAAATTAAGGAAACTAAATCAGAATATCCCTATGTATCAAGTTATGGGAAT
    GTCATAGAATTAGGGGAAGGAGATCTTTCAAAAAACAAACCAGACAATTTAACTAAAATG
    GAATCTGGTAAAATCTATTCTGATTCAGAAAAACAACAATATCTGTTAAAGGATAATATC
    ATTCTAAGAAAAGGCTATGCACTAAAAGTGACTACCTATAATCCTGGAAAAACGGATATG
    TTAGAAGGAAATGGAGTCTATAGCAAGGAAGATATAGCAAAAATACAAAAGGCCAATCCT
    AATCTAAGAGCCCTTTCAGAAACAACAATTTATGCTGATAGTAGAAATGTTGAAGATGGA
    AGAAGTACCCAATCTGTATTAATGTCGGCTTTGGACGGCTTTAACATTATAAGGTATCAA
    GTGTTTACATTTAAAATGAACGATAAAGGGGAAGCTATCGATAAAGACGGAAATCTTGTG
    ACAGATTCTTCTAAACTTGTATTATTTGGTAAGGATGATAAAGAATACACTGGAGAGGAT
    AAGTTCAATGTAGAAGCTATAAAAGAAGATGGCTCCATGTTATTTATTGATACCAAACCA
    GTAAACCTTTCAATGGATAAGAACTACTTTAATCCATCTAAATCTAATAAAATTTATGTA
    CGAAATCCAGAATTTTATTTAAGAGGTAAGATTTCTGATAAGGGTGGTTTTAACTGGGAA
    TTGAGAGTTAATGAATCGGTTGTAGATAATTATTTAATCTACGGAGATTTACACATTGAT
    AACACTAGAGATTTTAATATTAAGCTGAATGTTAAAGACGGTGACATCATGGACTGGGGA
    ATGAAAGACTATAAAGCAAACGGATTTCCAGATAAGGTAACAGATATGGATGGAAATGTT
    TATCTTCAAACTGGCTATAGTGATTTGAATGCTAAAGCAGTTGGAGTCCACTATCAGTTT
    TTATATGATAATGTTAAACCCGAAGTAAACATTGATCCTAAGGGAAATACTAGTATCGAA
    TATGCTGATGGAAAATCTGTAGTCTTTAACATCAATGATAAAAGAAATAATGGATTCGAT
    GGTGAGATTCAAGAACAACATATTTATGTAAATGGAAAAGAATATACATCATTTGATGAT
    ATTAAACAAATAACAGACAAGACACTAAACATTAAGATTGTTGTAAAAGATTTTGCAAGA
    AATACAACCGTAAAAGAATTCATTTTAAATAAAGATACGGGAGAGGTAAGTGAATTAAAA
    CCTCATAGGGTAACTGTGACCATTCAAAATGGAAAAGAAATGAGTTCAACGATAGTGTCG
    GAAGAAGATTTTATTTTACCTATTTATAAGGGTGAATTAGAAAAAGGATACCAATTTGAT
    GGTTGGAAAATTTCTGGTTTCGAAGGTAAAAAAGACGCTGGCTATGTTATTAATCTATCA
    AAAGATACCTTTATAAAACCTGTATTCAAGAAAATAGAGGAGAAAAAGGAGGAAGAAAAT
    AAACCTACTTTTGATGTATCGAAAAAGAAAGATAACCCACAAGTAAACCATAGTCAATTA
    AATGAAAGTCACAGAAAAGAGGATTTACAAAGAGAAGATCATTCACAAAAATCTGATTCA
    ACTAAGGATGTTACAGCTACAGTTCTTGATAAAAACAATATCAGTAGTAAATCAACTACT
    AACAATCCTAATAAGTTGCCAAAAACTGGAACAGCAAGCGGAGCCCAGACACTATTAGCT
    GCCGGAATAATGTTTATAGTAGGAATTTTTCTTGGATTGAAGAAAAAAAATCAAGATTAA
    60
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    6300
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    6420

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN994038_RS03090 [old locus tag: SPN994038_05790 ]
  • symbol: SPN994038_RS03090
  • description: S8 family serine peptidase
  • length: 2139
  • theoretical pI: 6.35826
  • theoretical MW: 240120
  • GRAVY: -0.730108

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 63.7)
    Genetic information processing Protein fate Protein modification and repair type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 63.7)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 23.9)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Peptidase_S8; Subtilase family (PF00082; HMM-score: 123.4)
    E-set (CL0159) fn3_5; Fn3-like domain (PF06280; HMM-score: 110.2)
    and 3 more
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 27.2)
    Leu-IlvD (CL0364) PA; PA domain (PF02225; HMM-score: 24)
    PPP-I (CL0570) Inhibitor_I9; Peptidase inhibitor I9 (PF05922; HMM-score: 21.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helix: 1
  • SignalP: Signal peptide SP(Sec/SPI) length 27 aa
    • SP(Sec/SPI): 0.962285
    • TAT(Tat/SPI): 0.00371
    • LIPO(Sec/SPII): 0.02617
    • Cleavage Site: CS pos: 27-28. VLA-DT. Pr: 0.8995
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000750037 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKSTVLSLTTAAVILAAYAPNEVVLADTSNSEDALSISDKEKVAENKEKHENIHSAMETSQDFKEKKTAVIKEKEVVSKNPVIDNNTSNEEAKIKEENSNQSQGDYTDSFVNKNTENPKKQDKVVYIAEFKDKESGEKAIKQLSSLKNTKVLYTYDRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDKVNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIALQNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGKQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGKPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAGSTSGSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHFIRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQGRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISYYLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLFNIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGTDLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKATKYDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKSEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRALSETTIYADSRNVEDGRSTQSVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKFNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPIYKGELEKGYQFDGWKISGFEGKKDAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGLKKKNQD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

G Bethe, R Nau, A Wellmer, R Hakenbeck, R R Reinert, H P Heinz, G Zysk
The cell wall-associated serine protease PrtA: a highly conserved virulence factor of Streptococcus pneumoniae.
FEMS Microbiol Lett: 2001, 205(1);99-104
[PubMed:11728722] [WorldCat.org] [DOI] (P p)Shaper Mirza, Landon Wilson, William H Benjamin, Jan Novak, Stephen Barnes, Susan K Hollingshead, David E Briles
Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.
Infect Immun: 2011, 79(6);2440-50
[PubMed:21422179] [WorldCat.org] [DOI] (I p)Sacha F de Stoppelaar, Hester J Bootsma, Aldert Zomer, Joris J T H Roelofs, Peter W M Hermans, Cornelis van 't Veer, Tom van der Poll
Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.
PLoS One: 2013, 8(11);e80062
[PubMed:24244609] [WorldCat.org] [DOI] (I e)

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