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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-JAN-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_0630 [new locus tag: SPAP_RS03120 ]
  • pan locus tag?: PNEUPAN001574000
  • symbol: SPAP_0630
  • pan gene symbol?: prtA
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_0630 [new locus tag: SPAP_RS03120 ]
  • symbol: SPAP_0630
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 593771..599614
  • length: 5844
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
    5761
    5821
    ATGATGAATCATGCCAGAAAGGAAATTGGAGTTGAGGAAGCTATTGATTACCTAAAGTCT
    ATCAATGCTCCGTTTGGGAAAAATTTTGATGGTAGAGGTATGGTCATTTCAAATATCGAT
    ACTGGAACAGATTATAGACATAAGGCTATGAGAATCGATGATGATGCCAAAGCCTCAATG
    AGATTTAAAAAAGAAGACTTAAAAGGTACTGATAAAAATTATTGGTTGAGTGATAAAATC
    CCTCATGCGTTCAATTATTATAATGGTGGCAAAATCACTGTAGAAAAATATGATGATGGA
    AGGGATTATTTTGACCCACATGGGATGCATATTGCAGGGATTCTTGCTGGAAATGATACT
    GAACAAGATATCAAAAACTTTAACGGCATAGATGGAATTGCACCTAATGCACAAATTTTC
    TCTTACAAAATGTATTCTGACGCAGGATCTGGGTTTGCGGGTGATGAAACAATGTTTCAT
    GCTATTGAAGATTCTATCAAACACAACGTTGATGTTGTTTCGGTATCATCTGGTTTTACA
    GGAACAGGTCTTGTAGGTGAGAAATATTGGCAAGCTATTAGGGCATTAAGAAAAGCAGGC
    ATTCCAATGGTTGTCGCTACGGGTAACTATGCGACTTCTGCTTCAAGTTCTTCATGGGAT
    TTAGTAGCAAATAATCATCTGAAAATGACCGACACTGGAAATGTAACACGAACTGCAGCA
    CATGAGGATGCGATAGCGGTCGCTTCTGCTAAAAATCAAACAGTTGAGTTTGATAAAGTT
    AACATAGGTGGAGAAAGTTTTAAATACAGAAATATAGGGGCCTTTTTCGATAAGAATAAA
    ATCACAACAAATGAAGATGGAACAAAAGCTCCTAGTAAATTAAAATTTGTATATATAGGC
    AAGGGGCAAGACCAAGATTTGATAGGTTTGGATCTTAGGGGCAAAATTGCAGTAATGGAT
    AGAATTTATACAAAGGATTTAAAAAATGCTTTTAAAAAAGCTATGGATAAGGGTGCACGC
    GCCATTATGGTTGTAAATACTGTAAATTACTACAATAGAGATAATTGGACAGAGCTTCCA
    GCTATGGGATATGAAGCGGATGAAGGTACTAAAAGTCAAGTGTTTTCAATTTCAGGAGAT
    GATGGTGTAAAGCTATGGAACATGATTAATCCTGATAAAAAAACTGAAGTCAAAAGAAAT
    AATAAAGAAGATTTTAAAGATAAATTGGAGCAATACTATCCAATTGATATGGAAAGTTTT
    AATTCCAACAAACCGAATGTAGGTGACGAAAAAGAGATTGACTTTAAGTTTGCACCTGAC
    ACAGACAAAGAACTCTATAAAGAAGATATCATCGTTCCAGCAGGATCTACATCTTGGGGG
    CCAAGAATAGATTTACTTTTAAAACCCGATGTTTCAGCACCTGGTAAAAATATTAAATCC
    ACGCTTAATGTTATTAATGGCAAATCAACTTATGGCTATATGTCAGGAACTAGTATGGCG
    ACTCCAATCGTGGCAGCTTCTACTGTTTTGATTAGACCGAAATTAAAGGAAATGCTTGAA
    AGACCTGTATTGAAAAATCTTACGGGAGATGACAAAATAGATCTTACAAGTCTTACAAAA
    ATTGCCCTACAAAATACTGCGCGACCTATGATGGATGCAACTTCTTGGAAAGAAAAAAGT
    CAATACTTTGCATCACCTAGACAACAGGGAGCAGGCCTAATTAATGTGGCCAATGCTTTG
    AGAAATGAAGTTGTAGCAACTTTCAAAAACACTGATTCTAAAGGTTTGGTAAACTCATAT
    GGTTCCATTTCTCTTAAAGAAATAAAAGGTGATAAAAAATACTTTACAATCAAGCTTCAC
    AATACATCAAACAGACCTTTGACTTTTAAAGTTTCAGCATCAGCGATAACTACAGATTCT
    CTAACTGACAGATTAAAACTTGATGAAACATATAAAGATGAAAAATCTCCAGATGGTAAG
    CAAATTGTTCCAGAAATTCACCCAGAAAAAGTCAAAGGAGCAAATATCACATTTGAGCAT
    GATACTTTCACTATAGGCGCAAATTCTAGCTTTGATTTGAATGCGGTTATAAATGTTGGA
    GAGGCCAAAAACAAAAATAAATTTGTAGAATCATTTATTCATTTTGAGTCAGTGGAAGAA
    ATGGAAGCTCTAAACTCCAACGGGAAGAAAATAAACTTCCAACCTTCTTTGTCGATGCCT
    CTAATGGGATTTGCTGGGAATTGGAACCACGAACCAATCCTTGATAAATGGGCTTGGGAA
    GAAGGGTCAAGATCAAAAACACTGGGAGGTTATGATGATGATGGTAAACCGAAAATTCCA
    GGAACCTTAAATAAGGGAATTGGTGGAGAACATGGTATAGATAAATTTAATCCAGCAGGA
    GTTATACAAAATAGAAAAGATAAAAATACAACATCCCTGGATCAAAATCCAGAATTATTT
    GCTTTCAATAACGAAGGGATCAACGCTCCATCATCAAGTGGTTCTAAGATTGCTAACATT
    TATCCTTTAGATTCAAATGGAAATCCTCAAGATGCTCAACTTGAAAGAGGATTAACACCT
    TCTCCACTTGTATTAAGAAGTGCAGAAGAAGGATTGATTTCAATAGTAAATACAAATAAA
    GAGGGAGAAAATCAAAGAGACTTAAAAGTCATTTCGAGAGAACACTTTATTAGAGGAATT
    TTAAATTCTAAAAGCAATGATGCAAAGGGAATCAAATCATCTAAACTAAAAGTTTGGGGT
    GACTTGAAGTGGGATGGACTCATCTATAATCCTAGAGGTAGAGAAGAAAATGCACCAGAA
    AGTAAGGATAATCAAGATCCTGCTACTAAGATAAGAGGTCAATTTGAACCGATTGCGGAA
    GGTCAATATTTCTATAAATTTAAATATAGATTAACTAAAGATTACCCATGGCAGGTTTCC
    TATATTCCTGTAAAAATTGATAACACCGCCCCTAAGATTGTTTCGGTTGATTTTTCAAAT
    CCTGAAAAAATTAAGTTGATTACAAAGGATACTTATCATAAGGTAAAAGATCAGTATAAG
    AATGAAACGCTATTTGCGAGAGATCAAAAAGAACATCCTGAAAAATTTGACGAGATTGCG
    AACGAAGTTTGGTATGCTGGCGCCGCTCTTGTTAATGAAGATGGAGAGGTTGAAAAAAAT
    CTTGAAGTAACTTACGCAGGTGAGGGTCAAGGAAGAAATAGAAAACTTGACAAAGACGGA
    AATACCATTTATGAAATTAAAGGTGCGGGAGATTTAAGGGGAAAAATCATTGAAGTCATT
    GCATTAGATGGTTCTAGCAATTTCACAAAGATTCATAGAATTAAATTTGCTAATCAGGCT
    GATGAAAAGGGGATGATTTCCTATTATCTAGTAGATCCTGATCAAGATTCATCTAAATAT
    CAAAAGCTTGGCGAGATTGCAGAATCTAAATTTAAAAATTTAGGAAATGGAAAAGAGGGT
    AGTCTAAAAAAAGATACAACTGGGGTAGAACATCATCATCAAGAAAATGAAGAGTCTATT
    AAAGAAAAATCTAGTTTTACTATTGATAGAAATATTTCAACAATTAGAGACTTTGAAAAT
    AAAGACCTAAAGAAACTCATTAAAAAGAAATATAAGGAAGAAGACGACTTTGTAACTGGT
    GGAAAAAGAACAGTAGAACTTGATTATAAATATGACGATAAAGGAAATATAACTGCCTAT
    GAAGATGAAAGTGCTCTAGAATATGAAACTGAAAAATTTGACGAAATAAAATCAAAAATT
    TATGGTGTTCTAAGCCCATCTAAAGATGGACACTTTGAAATTCTTGGAAAGATAAGCAAT
    GTTTCTAAAAATGCCAAGGTATATTATGGAAATAACTATAAATTTATAGAAATCAAAGCG
    ACTAAGTATGACTCACATTCAAAAACGATGATATTTGATTTATACGCTAATATTAATGAT
    ATTGTAGATGGATTAGCTTTTGCTGGAGATATGAGATTATTTGTTAAAGATGACAATCAA
    ATAAAAGCTGAAACTAAAATTAGAATGCCTGAAAAAAATAAGGAAACTAAAGCAGAATAT
    CCGTATGTATCAAGTTATGGGAATGTAATCGAATTAGGAGAAGGAGACCTTTCAAAAAAC
    AAACCAGACAATTTAACTAAAATGGAATCTGGTAAAATCTATTCTGATTCAGAAAAACAA
    CAATATCTGTTAAAGGATAACATCATTCTAAGAAAAGGCTATGCACTAAAAGTGACTACC
    TATAATCCTGGAAAAACGGATATGTTAGAAGGAAATGGAGTCTATAGCAAGGAAGATATA
    GCAAAAATACAAAAGGCCAATCCTAATCTAAGAGTCCTTTCAGAAACAACAATTTATGCT
    GATAGTAGAAATGTTGAAGATGGAAGAAGTACCCAAGCTGTATTAATGTCGGCTTTGGAC
    GGCTTTAACATTATAAGGTATCAAGTGTTTACATTTAAAATGAACGATAAAGGGGAAGCT
    ATCGATAAAGACGGAAATCTTGTGACAGATTCTTCTAAACTTGTATTATTTGGTAAGGAT
    GATAAAGAATACACTGGAGAGGATAAGTCCAATGTAGAAGCTATAAAAGAAGATGGCTCC
    ATGTTATTTATTGATACCAAACCAGTAAACCTTTCAATGGATAAGAACTACTTTAATCCA
    TCTAAATTTAATAAAATTTATGTACGAAATCCAGAATTTTATTTAAGAGGTAAGATTTCT
    GATAAGGGTGGTTTTAACTGGGAATTGAGAGTTAATGAATCGGTTGTAGATAATTATTTA
    ATCTACGGAGATTTACACATTGATAACACTAGAGATTTTAATATTAAGCTGAATGTTAAA
    GACGGTGACATCATGGACTGGGGAATGAAAGACTATAAAGCAAACGGATTTCCAGATAAG
    GTAACAGATATGGATGGAAATGTTTATCTTCAAACTGGCTATAGTGATTTGAATGCTAAA
    GCAGTTGGAGTCCACTATCAGTTTTTATATGATAATGTTAAACCCGAAGTAAACATTGAT
    CCTAAGGGAAATACTAGTATCGAATATGCTGATGGAAAATCTGTAGTCTTTAACATCAAT
    GATAAAAGAAATAATGGATTCGATGGTGAGATTCAAGAACAACATATTTATATAAATGGA
    AAAGAATATACATCATTTGATGATATTAAACAAATAATAGACAAGACACTAAACATTAAG
    ATTGTTGTAAAAGATTTTGCAAGAAATACAACCGTAAAAGAATTCATTTTAAATAAAGAT
    ACGGGAGAGGTAAGTGAATTAAAACCTCATAGGGTAACTGTGACCATTCAAAATGGAAAA
    GAAATGAGTTCAACGATAGTGTCGGAAGAAGATTTTATTTTACCTGTTTATAAGGGTGAA
    TTAGAAAAAGGATACCAATTTGATGGTTGGGAAATTTCTGGTTTCGAAGGTAAAAAAGAC
    GCTGGCTATGTTATTAATCTATCAAAAGATACCTTTATAAAACCTGTATTCAAGAAAATA
    GAGGAGAAAAAGGAGGAAGAAAATAAACCTACTTTTGATGTATCGAAAAAGAAAGATAAC
    CCACAAGTAAACCATAGTCAATTAAATGAAAGTCACAGAAAAGAGGATTTACAAAGAGAA
    GAGCATTCACAAAAATCTGATTCAACTAAGGATGTTACAGCTACAGTTCTTGATAAAAAC
    AATATCAGTAGTAAATCAACTACTAACAATCCTAATAAGTTGCCAAAAACTGGAACAGCA
    AGCGGAGCCCAGACACTATTAGCTGCCGGAATAATGTTTATAGTAGGAATTTTTCTTGGA
    TTGAAGAAAAAAAATCAAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
    4560
    4620
    4680
    4740
    4800
    4860
    4920
    4980
    5040
    5100
    5160
    5220
    5280
    5340
    5400
    5460
    5520
    5580
    5640
    5700
    5760
    5820
    5844

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_0630 [new locus tag: SPAP_RS03120 ]
  • symbol: SPAP_0630
  • description: hypothetical protein
  • length: 1947
  • theoretical pI: 6.32355
  • theoretical MW: 218821
  • GRAVY: -0.719209

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 64.2)
    Genetic information processing Protein fate Protein modification and repair type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 64.2)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 24.1)
  • TheSEED  :
    • C5a peptidase precursor (EC 3.4.21.-)
  • PFAM:
    no clan defined Peptidase_S8; Subtilase family (PF00082; HMM-score: 124.3)
    E-set (CL0159) fn3_5; Fn3-like domain (PF06280; HMM-score: 110.8)
    and 3 more
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 27.2)
    Leu-IlvD (CL0364) PA; PA domain (PF02225; HMM-score: 24.1)
    no clan defined DUF6061; Family of unknown function (DUF6061) (PF19537; HMM-score: 13.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helix: 1
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005669
    • TAT(Tat/SPI): 0.000502
    • LIPO(Sec/SPII): 0.0008
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM84223 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MMNHARKEIGVEEAIDYLKSINAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLTGDDKIDLTSLTKIALQNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNEGINAPSSSGSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAYEDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKETKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKFNKIYVRNPEFYLRGKISDKGGFNWELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDGEIQEQHIYINGKEYTSFDDIKQIIDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREEHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGLKKKNQD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

G Bethe, R Nau, A Wellmer, R Hakenbeck, R R Reinert, H P Heinz, G Zysk
The cell wall-associated serine protease PrtA: a highly conserved virulence factor of Streptococcus pneumoniae.
FEMS Microbiol Lett: 2001, 205(1);99-104
[PubMed:11728722] [WorldCat.org] [DOI] (P p)Shaper Mirza, Landon Wilson, William H Benjamin, Jan Novak, Stephen Barnes, Susan K Hollingshead, David E Briles
Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.
Infect Immun: 2011, 79(6);2440-50
[PubMed:21422179] [WorldCat.org] [DOI] (I p)Sacha F de Stoppelaar, Hester J Bootsma, Aldert Zomer, Joris J T H Roelofs, Peter W M Hermans, Cornelis van 't Veer, Tom van der Poll
Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.
PLoS One: 2013, 8(11);e80062
[PubMed:24244609] [WorldCat.org] [DOI] (I e)

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