From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_RS12545
  • pan locus tag?: PNEUPAN001574000
  • symbol: SPNA45_RS12545
  • pan gene symbol?: prtA
  • synonym:
  • product: LPXTG cell wall anchor domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS, pseudogene
  • locus tag: SPNA45_RS12545
  • symbol: SPNA45_RS12545
  • product: LPXTG cell wall anchor domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1480572..1483699
  • length: 3128
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_018594 (1480572..1483699) NCBI
  • BioCyc: SPNA45_RS12545 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0558 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    TTGAAGTGGGATGGACTTATCTATAATCCTAGAGGTAGAGAAGAAAATGCACCAGAAAGT
    AAGGATAATCCAGATCCTGCTACTAAGATAAGAGGTCAATTTGAACCGATTGCGGAAGGT
    CAATATTTCTATAAATTTAAATATAGATTAACTAAAGATTACCCATGGCAGGTTTCCTAT
    ATTCCTGTAAAAATTGATAACACCGCCCCTAAGATTGTTTCGGTTGATTTTTCAAATCCT
    GAAAAAATTAAGTTGATTACAAAGGATACTTATCATAAGGTAAAAGATCAGTATAAGAAT
    GAAACGCTATTTGCGAGAGATCAAAAAGAACATCCTGAAAAATTTGACGAGATTGCGAAC
    GAAGTTTGGTATGCTGGCGCCGCTCTTGTTAATGAAGATGGAGAGGTTGAAAAAAATCTT
    GAAGTAACTTACGCAGGTGAGGGTCAAGGAAGAAATAGAAAACTTGATAAAGACGGAAAT
    ACCATTTATGAAATTAAAGGTGCGGGAGATTTAAGGGGAAAAATCATTGAAGTCATTGCA
    TTAGATGGTTCTAGCAATTTCACAAAGATTCATAGAATTAAATTTGCTAATCAGGCTGAT
    GAAAAGGGGATGATTTCCTATTATCTAGTAGATCCTGATCAAGATTCATCTAAATATCAA
    AAGCTTGGCGAGATTGCAGAATCTAAATTTAAAAATTTAGGAAATGGAAAAGAGGGTAGT
    CTAAAAAAAGATACAACTGGGGTAGAACATCATCATCAAGAAAATGAAGAGTCTATTAAA
    GAAAAATCTAGTTTTACTATTGATAGAAATATTTCAACAATTAGAGACTTTGAAAATAAA
    GACCTAAAGAAACTCATTAAAAAGAAATTTAGAGAAGTTGATGATTTTACAAGTGAAACT
    GGTAAGAGAATAGAGGAATACGATTATAAATACGATGATAAGGGAAATATTATTGCTTAT
    GACGATGGTAGTGCCTTACAATATGAAACTGAAAAACTTGACGAAATAAAATCAAAAATT
    TATGGCGTTCTAAGCCCATCTAAAGATGGACACTTTGAAATTCTTGGAAAGATAAGCAAT
    GTTTCTAAAAATGCCAAGGTATATTATGGAAATAGCTATAAATCGATAGAAATCAAAGCG
    ACTAAGTATGACTCACATTCAAAAACGATGACATTTGATTTATACGCTAATATTAATGAT
    ATTGTGGATGGATTAGCTTTTGCTGGAGATATGCGGTTTTTTGTTAAAGATGATGATCGA
    ATAAAAGCTGAAACTAAAATTAGAATGCCTGAAAAAATAAGGAAACTAAAGCAGAATATC
    CCTATGTATCAAGTTATGGGAATGTAATCGAATTAGGAGAAGGAGATCTTTCAAAGAACA
    AACCAGACAATTTAACTAAAATGGAATCTGGTAAAATCTATTCTGATTCAGAAAAACAAC
    AATATCTGTTAAAGGATAACATCATTCTAAGAAAAGGCTATGCACTAAAAGTGACTACCT
    ATAATCCTGGAAAAACGGATATGTTAGAAGGAAATGGAGTCTATAGCAAGGAAGATATAG
    CAAAAATACAAAAGGCCAATCCTAATCTAAGAGTCCTTTCAGAAACAACAATTTATGCTG
    ATAGTAGAAATGTTGAAGATGGAAGAAGTACCCAAGCTGTATTAATGTCGGCTTTGGACG
    GCTTTAACATTATAAGGTATCAAGTGTTTACATTTAAAATGAACGATAAAGGGGAAGCTA
    TCGATAAAGACGGAAATCTTGTGACAGATTCTTCTAAACTTGTATTATTTGGTAAGGATG
    ATAAGGAATACACTGGAGAGGATAAGTCCAATGTAGAAGCTATAAAAGAAGATGGCTCCA
    TGTTATTTATTGATACCAAACCAGTAAACCTTTCAATGGATAAGAACTACTTTAATCCAT
    CTAAATCTAATAAAATTTATGTACGAAATCCAGAATTTTATTTAAGAGGTAAGATTTCTG
    ATAAGGGTGGTTTTAACTGGGAATTGAGAGTTAATGAATCGGTTGTAGATAATTATTTAA
    TCTACGGAGATTTACACATTGATAACACTAGAGATTTTAATATTAAGCTGAATGTTAAAG
    ACGGTGACATCATGGACTGGGGAATGAAAGACTATAAAGCAAACGGATTTCCAGATAAGG
    TAACAGATATGGATGGAAATGTTTATCTTCAAACTGGCTATAGCGATTTGAATGCTAAAG
    CAGTTGGAGTCCACTATCAGTTTTTATATGATAATGTTAAACCCGAAGTAAACGTTGATC
    CTAAGGGAAATACTAGTATCGAATATGCTGATGGAAAATCTGTAGTCTTTAACATCAATG
    ATAAAAGAAATAATGGATTCGATGGTGAGATTCAAGAACAACATATTTATGTAAATGGAA
    AAGAATATACATCATTTGATGATATTAAACAAATAACAGACAAGACACTAAACATTAAGA
    TTGTTGTAAAAGATTTTGCAAGAAATACAACCGTAAAAGAATTCATTTTAAATAAAGATA
    CGGGAGAGGTAAGTGAATTAAAACCTCATAGGGTAACTGTGACCATTCAAAATGGAAAAG
    AAATGAGTTCAACGATAGTGTCGGAAGAAGATTTTATTTTACCTGTTTATAAGGGTGAAT
    TAGAAAAAGGATACCAATTTGATGGTTGGGAAATTTCTGGTTTCGAAGGTAAAAAAGACG
    CTGGCTATGTTATTAATCTATCAAAAGATACCTTTATAAAACCTGTATTCAAGAAAATAG
    AGGAGAAAAAGGAGGAAGAAAATAAACCTACTTTTGATGTATCGAAAAAGAAAGATAACC
    CACAAGTAAACCATAGTCAATTAAATGAAAGTCATAGAAAAGAGGATTTACAAAGAGAAG
    ATCATTCACAAAAATCTGATTCAACTAAGGATGTTACAGCTACAGTTCTTGATAAAAACA
    ATATCAGTAGTAAATCAACTACTAACAATCCTAATAAGTTGCCAAAAACTGGAACAGCAA
    GCGGAGCCCAGACACTATTAGCTGCCGGAATAATGTTTATAGTAGGAATTTTTCTTGGAT
    TGAAGAAAAAAATCAAGATTAAGACAAAAGCTATAGAAAAAAATGGTTTATGTACTGAGA
    TTAGATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3128

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_RS12545
  • symbol: SPNA45_RS12545
  • description: LPXTG cell wall anchor domain-containing protein
  • length:
  • theoretical pI:
  • theoretical MW:
  • GRAVY:

⊟Function[edit | edit source]

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb:
  • SignalP:
  • predicted transmembrane helices (TMHMM):

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

G Bethe, R Nau, A Wellmer, R Hakenbeck, R R Reinert, H P Heinz, G Zysk
The cell wall-associated serine protease PrtA: a highly conserved virulence factor of Streptococcus pneumoniae.
FEMS Microbiol Lett: 2001, 205(1);99-104
[PubMed:11728722] [WorldCat.org] [DOI] (P p)Shaper Mirza, Landon Wilson, William H Benjamin, Jan Novak, Stephen Barnes, Susan K Hollingshead, David E Briles
Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.
Infect Immun: 2011, 79(6);2440-50
[PubMed:21422179] [WorldCat.org] [DOI] (I p)Sacha F de Stoppelaar, Hester J Bootsma, Aldert Zomer, Joris J T H Roelofs, Peter W M Hermans, Cornelis van 't Veer, Tom van der Poll
Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.
PLoS One: 2013, 8(11);e80062
[PubMed:24244609] [WorldCat.org] [DOI] (I e)

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPNA45_RS12545&oldid=155444"