From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV104
  • locus tag: INV104_RS03260 [old locus tag: INV104_05550 ]
  • pan locus tag?: PNEUPAN001606000
  • symbol: INV104_RS03260
  • pan gene symbol?: zmpB
  • synonym:
  • product: G5 domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: INV104_RS03260 [old locus tag: INV104_05550 ]
  • symbol: INV104_RS03260
  • product: G5 domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 625823..631510
  • length: 5688
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_017591 (625823..631510) NCBI
  • BioCyc: INV104_RS03260 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0577 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    GTGTTTAAAAAAGACCGTTTTTCAATTCGTAAGATTAAGGGAGTTGTAGGCTCTGTATTT
    CTTGGAAGCCTTTTGATGGCTCCTTCTGTAGTGGACGCAGCTACCTATCACTATGTAAAT
    AAAGAGATTATTTCACAAGAAGCTAAAGATTTAATTCAGACAGGAAAGCCTGACAGGAAT
    GAAGTTGTATATGGTTTGGTGTATCAAAAAGATCAGTTGCCTCAAACAGGGACAGAAGCA
    TCTGTTTTGACAGCTTTTGGTTTGCTGACTGTTGGGAGCTTGCTTTTAATCTACAAGAGA
    AAGAAAATTGCTAGCGTCTTTCTAGTTGGAGCTATGGGATTGGTAGTTCTTCCTAGTGCA
    GGGGCTGTAGACCCAGTTGCGACCTTAGCGCTGGCTAGTCGAGAGGGTGTTGTTGAAATG
    GATGGCTATCGCTATGTTGGTTATCTATCAGGTGACATCCTCAAAACGCTTGGCTTGGAC
    ACTGTTTTAGAAGAAACCTCAGCAAAACCTGGAGAGGTGACTGTAGTCGAAGTTGAGACT
    CCTCAATCAACAACAAATCAGGAGCAAGCTAGGACAGAAAACCAAGTAGTAGAGACAGAG
    GAAACTCCAAAAGAAGAAGCACCTAGAACAGAAGAAAGTCCAAAGGAAGAACCAAAATCG
    GAGGTAAAACCTACTGACGACACCCTTCCTAAAGTAGAAGAGGGGAAAGAAGATTCAGCA
    GAACCAGCTCCAGTTGAAGAAGTAGGTGGAGAAGTTGAGTCAAAATCAGAGGAAAAAGTA
    GCAGTTAAGCCAGAAAGTCAACCATCAGACAAACCAGCTGAGGAATCAAAAGTTGAACCA
    CCAGTAGAACAAGCAAAAGTCCCAGAACAACCCGTGCAACCTACACAAGCTGAGCAACCA
    AGTACACCAAAAGAATCATCACAAGAAGACAATCCTAAAGAAGATAGGGGAGCGGAAGAG
    ACACCGAAACAAGAAGAGTCAACTCCAGATACCAAGGCTGAAGAAACTGTAGAACCAAAA
    GAGGAGACTAAAACAGCTAAGGGGACGCAAGAAGAAGATTACGTGGGTGAGGCTCTTGTT
    CCAGAACAATTACCTGAGTATAAGGTGACTGAAGGAACACTCGTTGAAGAATCAACTACA
    GAACTTGACTATAAAACTGAAACGACTGAGGACCCAACCAAGTACACGGACGAAGAAACT
    GTCCTACGAAATGGTGAAAAAGGAAGTCAAGTTACAAAAACAACCTATAAAACAATAGGA
    GGGGTTAAAACTGACCAAGTTCTTTCAACCAGTACGGAAGTCACCAAGGAGCCTGTAAAT
    CAACAGGTAATCCGTGGTACAAAACCAATTGAAGGGACAACGGTTGAGACAAGAGAAGAA
    ATCATTCCTTTTGAAACAAAAGAACAAGAAGATGACACTTTAAAACGCGGAACAAGACAA
    GTAACTCAAGAAGGTGTAAACGATAAGAAACAAATTACTGAAACCTATAAAACAATTCGC
    GGAGAAAAAACAAGTGACGCTCCTACTATCACAGAAACAGTGATTGAAAAACCTCAAGAC
    AAAATTATTAAGAATGGCACAAAAGAGTTAGAGAAACCAACCTTGGAATGGGCTAAAACA
    GATAAAGATGTCTTGAAGAAGAGTGCGACAGCTAGTTATACATTGACTAAACCAGCTGGA
    GTAGAAATTAAATCGATTAAAGTAGCTCTAAAAGATAATACTGGAACAGTTGTTAAAGAA
    GTAACGGTAGAAGAAAATAACTTACAAGCTACTTTAGACAACTTGAAATATTATCAAGGT
    TATACACTATCCACAACCATGGTCTATGATCGAGGTAACGGTGAAGAAACTGAAATATTA
    GAAGATAAAGAAGTTCAGTTAGACCTTAAAAAAGTTGAGATTAAAGATATTAAAGAAACA
    AGATTGATGAAAGTGGATGAGAATGGAAATGAAACAGATAGTAGCCTTCTAGAAACTGTT
    CCAGAAAATCTAACGTCATATTATCTAAAAATTACCACTAATCATAATAAAGTAACAAGG
    CTTGCCATTACTAATATAGAGGAAGTAACTGAGGAGGAGACATCCTTATTTAAAGTTACT
    GCTTCAGCTCCTGATTTAATCCAACGTGATTCAAATAATAGTTTGAGTCAAACATACACT
    TATTACATAGAGAAACCCAAAGCATCGCAAAATAACGTTTACTATAACTTCAAAGATTTA
    GTAGATGCTATGCAGAAAAATCCTAACGGTGAGTTTAAATTAGGATCGGATTTAAATGCA
    ACAAATGTACCTACACCAAGTAAATCATATGTAACAGGTAAATTTACAGGTCACTTAACA
    AGTGTTGATGGTAAGCATTTCTCCATTCATAACACTGCTCGTCCATTATTTGATAGAGTT
    GAAGGGGGTTCTATCAAAAATATTAATTTAATTAACGTTAATATTAATATGCCTTGGGCA
    AATCAATTAGCTTCATTAGCTCAAACAGTGAAAAATGCAACTGTTGAAAATATTAAAGTA
    ACGGGTACTATCGTTGGTAATAACAATGTTGCGGGTATTTTGGATAAATTAGATGATGCA
    GGTATTATGACTAATGTTGCTTTTATCGGAAAAGTTCAATCTGTTGGTGATAAAGGGTGG
    AACTTGGCTGGGATTGCATCTGAGATTTATCGAGGCAATTTAAATAAAGCTTATGCAGAT
    GTTGAACTTAAAGGTTTAAATACTCGTGCAGGTGCTATAGTAGGACATTTAGCTCATGAT
    TTTAATCCAAGAGATGTTGGTGCTTGGTCTAATGTAAGAAATTCTGTAGCCAAAGGTACT
    ATTGATGTTGCTAGAGGTGATGTAGGCGGTTTAATTGGTAAAGACTGGCCTTGGGGAACC
    ATTGATAACAATATCAGCTTAGTGAATGTTAAGCGTGGTGATATTTTCTTTGGTTCTAAT
    GATATGGATGATGAATTTGTAAGCAATTGGATTAAACCTAATAATGCAACAGTTATCGGT
    GTGAGTTCTGGAGATAAAACCCATAAACAATCGTCTAAAATTAAAGAAATTTCACAGGTA
    GAAGCTGATAAGAAAATTAAGGATATGGGTATCACTGCTGATACATTTGAAGTAACTGAG
    CATTTGGTTGATAAGTTGAATCGCCGTATATTACGTGATGAAGAATACAAAACAATTCAA
    GATTATAATGCAAATCGTGAGCTTGTTTATCGTAATGTTGAAAAACTCCAACCGTTCTAC
    AACAAAGAATGGATTGTGAATCAAGGGAACAAGCTTACAACTGATAGTCCATTAATGAAT
    AAAGAAGTATTGTCTGTGACTGCAATGAAAGGTAATGACTTTATTACAGACCTTACAGAT
    GCTGACCATATTATGGTTCATTACGCAGATAAGACAAAAGATATCTTTACGATTTCTCCT
    AAAGACTCTCAAGTTAAGCAAGTAAAAGAATACAGTGTCGCAGAGCTTGGTGAAGTCGTC
    TATACACCAAATATGGTTGTTAAAGATCGTGCAGATTTAATTAGTGCTATTGAAGGTATT
    TTAAGTCCAATTGAATTACAATCTGATCCAATTTATCAACGATTAGGAAGAACTGGGGAT
    AACAGAGTTAATGCAATTAAGAATCTTTACTTAGAAGAAAGCTTTAAAGAAGTAAAAGAT
    CATCTTAATACATTTGTGACAAAATTAGTTGAAAATGAAGATCATCAACTGAATACAGAT
    GAAGCTGCAAAACGTGCCTTGATTAAGAAAATTGAAGATAACAAAGCTGCTGTCCTGTTA
    GGATTAACATACCTAAATCGTTATTACGGTGTGAAATTTGATAACTTCAATATTAAAGAA
    TTAATGCTATTCAAACCAGATTTTTATGGTAAGAATGTAAGTGTTTTAGATCGATTAATA
    GAAATTGGTTCAAAAGAGGACTATATTAAGGGAAGTCGTACACAGGAGTCCTTCCGTGAA
    GTGGTGGCGAAAAATACTCTTTCTGGAAACTTACATGACTTCTTGACCTACAATATGAAA
    CTATTCACAAATGAAACAGACATAAATGTTTGGTTTAAGAAAGCTATTGAAAATAATGCT
    TATGTAGTTGAACAACCGTCAACTAACCCTGCATTTGCTAATAAAAAATATCGTCTATAT
    GAAGGACTTAATAACGGACAACATGGACGCATGATTTTATCGCTTCTGAACTTGAAAGAT
    GCACATTTATTTATGATTTCAACATATAATACTATCTCATTTAGTTCGTTTGAAAAGTAT
    GGTAAAGATACAGAAGAAAAACGTGAATCGTTCAAGAGTGAAATCAATAAACGTGCTAAA
    GAGCAAGTTAATTACTTAGATTTTTGGTCACGCCTTGCCACTGATAATGTCCGCGATAAA
    CTTCTTAAGAGTCAAAATGTAGTTCCAACTCCTGTATGGGATAATCATGGTGCACCCGGT
    GGTTGGCCTGATAGATTTGGTCATCGAAAAGATAAACCGGATTATGCACCTATTCGTGAA
    TTCTTTGGACGTATTGATAAGTATCATGATTATAAGTATGGGTATGGAGCGTATGCTTAC
    ATCTTTGCTGATCCACAGCCTATGGATGCTGTATATTTTGTTATGTCGGATTTAATAAGT
    GAATATGGCACATCTGCCTTTACACATGAGACTACCCACGTAAATGACCGAATGGCATAT
    CTGGGAGGTCATAGACATCGACAGGGTACAGATCTTGAAGCATTTGCTCAAGGTATGTTA
    CAAACTCCAGCAGAACATGGACATCAAGGTGAATATGGCGCACTTGGATTAAATATGGCA
    TTTGAACGTTCAAATGATGGAAACCAATGGTATAATCCAGATCCTACCAAACTTCAAACA
    CGTGACCAAATCGACCATTACATGAAGAACTACAATGAAGCTATGATGATGCTCGATTAT
    GCAGAAGCTGAGGCTGTTCTTCCTAAGGTTAAAGGTGACAATAGTAAGTGGTTCAAGAAA
    ATTGATCGCGAAACACGTCGACCAATGGACAGAAATAAACTAAGTGGTCCTCACCAATGG
    GACAAAGTGCGTGATTTGATAGACGCTGAGAAAACAACTAACCTTGAAACCATCGATGAC
    TTGGTAAATAATAATTTCATGACCATTCACGGAAATCCAGGTAATAAGGTCTTCCACCCA
    GAGGACTTTGGTACGGCATATGTCAATGTTAATATGATGGCTGGTATTTATGGCGGTAAT
    ACGAGTCAAGGTGCCCCTGGTTCTCTATCCTTCAAACATAACGCCTTCCGTATGTGGGGT
    TACTATGGATATGAACATGGGTTCATTGACTATGTTTCAAGCAAACATCAAGGTGCAGCC
    AATAAAGAAAATAACGGTCTATTAGGTGATGATTTCATTATTAAGAAAGTTTCTAATAAC
    CAATTTTCAAACCTTGAAGATTGGAAGAAGCAATGGTATGGGGAAGTTCTTACAAAATCT
    AAAAAAGGTTTTGCACCAATTGAAATTAATGGCACTCAAATTTCAACCTATGAACAGTTG
    AAGACTATGTTTGATGAGGCTGTTACTAAAGATTTAACGGAACTAAACGATAGTAGTATT
    AAAGACAAATACCGAAATACAGTTGTCTTGAAATCGAAAGTCTTTAAAGCTCTCCTTAAA
    AACACAGACGGTTTCTCTGGTGATCTATTTACTGCACCACAAGCATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
    4560
    4620
    4680
    4740
    4800
    4860
    4920
    4980
    5040
    5100
    5160
    5220
    5280
    5340
    5400
    5460
    5520
    5580
    5640
    5688

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: INV104_RS03260 [old locus tag: INV104_05550 ]
  • symbol: INV104_RS03260
  • description: G5 domain-containing protein
  • length: 1895
  • theoretical pI: 4.98856
  • theoretical MW: 212671
  • GRAVY: -0.66686

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 26.4)
  • TheSEED: see INV104_05550
  • PFAM:
    no clan defined Peptidase_M26_C; M26 IgA1-specific Metallo-endopeptidase C-terminal region (PF07580; HMM-score: 774.6)
    and 6 more
    Peptidase_M26_N; M26 IgA1-specific Metallo-endopeptidase N-terminal region (PF05342; HMM-score: 291)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 71.1)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 29.9)
    E-set (CL0159) fn3; Fibronectin type III domain (PF00041; HMM-score: 15.3)
    no clan defined Glug; The GLUG motif (PF07581; HMM-score: 14.1)
    YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 10.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 2
  • SignalP: Signal peptide SP(Sec/SPI) length 33 aa
    • SP(Sec/SPI): 0.98483
    • TAT(Tat/SPI): 0.008282
    • LIPO(Sec/SPII): 0.001095
    • Cleavage Site: CS pos: 33-34. VDA-AT. Pr: 0.9782
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000472988 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEIISQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKKIASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLDTVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEETPKEEAPRTEESPKEEPKSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEESKVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNPKEDRGAEETPKQEESTPDTKAEETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDPTKYTDEETVLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPIEGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAPTITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSIKVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKEVQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLAITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDLVDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFDRVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDKLDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIVGHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKRGDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMGITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQGNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVKQVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVNAIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGLTYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFREVVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYRLYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRESFKSEINKRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPDYAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETTHVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQWYNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRPMDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKENNGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKTMFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Damiana Chiavolini, Guido Memmi, Tiziana Maggi, Francesco Iannelli, Gianni Pozzi, Marco R Oggioni
The three extra-cellular zinc metalloproteinases of Streptococcus pneumoniae have a different impact on virulence in mice.
BMC Microbiol: 2003, 3;14
[PubMed:12841855] [WorldCat.org] [DOI] (I e)C E Blue, G K Paterson, A R Kerr, M Bergé, J P Claverys, T J Mitchell
ZmpB, a novel virulence factor of Streptococcus pneumoniae that induces tumor necrosis factor alpha production in the respiratory tract.
Infect Immun: 2003, 71(9);4925-35
[PubMed:12933834] [WorldCat.org] [DOI] (P p)

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=INV104_RS03260&oldid=93308"